Role of Militarine in PM2.5-Induced BV-2 Cell Damage

A growing number of studies have shown that air fine particulate matter (PM 2.5 ) pollution is closely associated with neuroinflammation in humans. Militarine, a glucosyloxybenzyl 2-isobutylmalate compound isolated from Bletilla striata , has been found to exert significant neuroprotective effects....

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Veröffentlicht in:	Neurochemical research 2021-06, Vol.46 (6), p.1423-1434
Hauptverfasser:	Tian, Shu-Xin, Cheng, Wen, Lu, Jing-Jing, Zhou, Fang-Mei, Ding, Zhi-Shan, Zhu, Bing-Qi
Format:	Artikel
Sprache:	eng
Schlagworte:	Air pollution Antioxidants Apoptosis Biochemistry Biomedical and Life Sciences Biomedicine Cell Biology Cyclooxygenase-2 Cytokines Cytotoxicity Damage Gene expression Immunofluorescence Inflammation Interleukin 6 Membrane potential Microglia Mitochondria Neurochemistry Neurology Neuroprotection Neurosciences NF-κB protein Nuclear transport Original Paper Oxygenase Particulate matter Prostaglandin endoperoxide synthase Proteins Reactive oxygen species Receptors Signal transduction TLR4 protein Toll-like receptors Toxicity Translocation Tumor necrosis factor-α
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