Initial HCV infection of adult hepatocytes triggers a temporally structured transcriptional program containing diverse pro- and anti-viral elements

Transcriptional profiling provides global snapshots of virus-mediated cellular reprogramming, which can simultaneously encompass pro- and antiviral components. To determine early transcriptional signatures associated with HCV infection of authentic target cells, we performed ex vivo infections of ad...

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Veröffentlicht in:Journal of virology 2021-04, Vol.95 (10)
Hauptverfasser: Tegtmeyer, Birthe, Vieyres, Gabrielle, Todt, Daniel, Lauber, Chris, Ginkel, Corinne, Engelmann, Michael, Herrmann, Maike, Pfaller, Christian K, Vondran, Florian W R, Broering, Ruth, Vafadarnejad, Ehsan, Saliba, Antoine-Emmanuel, Puff, Christina, Baumgärtner, Wolfgang, Miskey, Csaba, Ivics, Zoltán, Steinmann, Eike, Pietschmann, Thomas, Brown, Richard J P
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Sprache:eng
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