Valvular changes after aortic valve neo‐cuspidization in children: A case series
Background Aortic valve neo‐cuspidization (AVNeo), a procedure wherein the aortic valve is reconstructed utilizing an autologous pericardium, has recently been more commonly performed in children. However, the postoperative morphological changes in the aortic valve of pediatric patients remain unkno...
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Veröffentlicht in: | Pediatrics international 2021-11, Vol.63 (11), p.1289-1296 |
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creator | Watanabe, Fumio Go, Kiyotaka Kojima, Taiki |
description | Background
Aortic valve neo‐cuspidization (AVNeo), a procedure wherein the aortic valve is reconstructed utilizing an autologous pericardium, has recently been more commonly performed in children. However, the postoperative morphological changes in the aortic valve of pediatric patients remain unknown. The current study aimed to describe the intraoperative and postoperative findings of aortic regurgitation (AR) and stenosis (AS) after AVNeo in children.
Methods
This case series describes the morphological changes in AR and AS, and their severity, between the perioperative period and 3 months postoperative period after AVNeo in children ( |
doi_str_mv | 10.1111/ped.14680 |
format | Article |
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Aortic valve neo‐cuspidization (AVNeo), a procedure wherein the aortic valve is reconstructed utilizing an autologous pericardium, has recently been more commonly performed in children. However, the postoperative morphological changes in the aortic valve of pediatric patients remain unknown. The current study aimed to describe the intraoperative and postoperative findings of aortic regurgitation (AR) and stenosis (AS) after AVNeo in children.
Methods
This case series describes the morphological changes in AR and AS, and their severity, between the perioperative period and 3 months postoperative period after AVNeo in children (<18 years) who underwent AVNeo between April 2016 and March 2020. Data were collected at two measurement points: (i) intraoperative transesophageal echocardiography after weaning from cardiopulmonary bypass (io‐TEE); (ii) postoperative transthoracic echocardiography 3 months after the procedure (po‐TTE).
Results
Seven patients were included in this case series. The number of postoperative AR sites and the ratio of AR jet area to the left ventricular outflow tract area showed a tendency to decrease between io‐TEE and po‐TTE. All AR sites were integrated during the postoperative period. One patient identified developed intraoperative AS, which maintained its severity after AVNeo.
Conclusions
Most cases exhibited spontaneous improvement in AR, while one developed postoperative AS. Further prospective investigation is, therefore, needed to explore surgical outcomes following AVNeo among children.</description><identifier>ISSN: 1328-8067</identifier><identifier>EISSN: 1442-200X</identifier><identifier>DOI: 10.1111/ped.14680</identifier><identifier>PMID: 33657683</identifier><language>eng</language><publisher>Australia: Blackwell Publishing Ltd</publisher><subject>Aortic valve ; aortic valve neo‐cuspidization ; aortic valve regurgitation ; aortic valve replacement ; Children ; Echocardiography ; Heart ; Heart surgery ; Morphology ; Patients ; pediatric ; Pediatrics ; Pericardium ; Postoperative period ; Regurgitation ; Stenosis ; transesophageal echocardiography ; Ventricle ; Weaning</subject><ispartof>Pediatrics international, 2021-11, Vol.63 (11), p.1289-1296</ispartof><rights>2021 Japan Pediatric Society</rights><rights>This article is protected by copyright. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3770-c5cc22156512c462305e151d2b6d31ac82d9e4b64a15688b732bf3893304088e3</citedby><cites>FETCH-LOGICAL-c3770-c5cc22156512c462305e151d2b6d31ac82d9e4b64a15688b732bf3893304088e3</cites><orcidid>0000-0002-7815-7185 ; 0000-0001-7136-9815 ; 0000-0001-9206-4033</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fped.14680$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fped.14680$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33657683$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Watanabe, Fumio</creatorcontrib><creatorcontrib>Go, Kiyotaka</creatorcontrib><creatorcontrib>Kojima, Taiki</creatorcontrib><title>Valvular changes after aortic valve neo‐cuspidization in children: A case series</title><title>Pediatrics international</title><addtitle>Pediatr Int</addtitle><description>Background
Aortic valve neo‐cuspidization (AVNeo), a procedure wherein the aortic valve is reconstructed utilizing an autologous pericardium, has recently been more commonly performed in children. However, the postoperative morphological changes in the aortic valve of pediatric patients remain unknown. The current study aimed to describe the intraoperative and postoperative findings of aortic regurgitation (AR) and stenosis (AS) after AVNeo in children.
Methods
This case series describes the morphological changes in AR and AS, and their severity, between the perioperative period and 3 months postoperative period after AVNeo in children (<18 years) who underwent AVNeo between April 2016 and March 2020. Data were collected at two measurement points: (i) intraoperative transesophageal echocardiography after weaning from cardiopulmonary bypass (io‐TEE); (ii) postoperative transthoracic echocardiography 3 months after the procedure (po‐TTE).
Results
Seven patients were included in this case series. The number of postoperative AR sites and the ratio of AR jet area to the left ventricular outflow tract area showed a tendency to decrease between io‐TEE and po‐TTE. All AR sites were integrated during the postoperative period. One patient identified developed intraoperative AS, which maintained its severity after AVNeo.
Conclusions
Most cases exhibited spontaneous improvement in AR, while one developed postoperative AS. Further prospective investigation is, therefore, needed to explore surgical outcomes following AVNeo among children.</description><subject>Aortic valve</subject><subject>aortic valve neo‐cuspidization</subject><subject>aortic valve regurgitation</subject><subject>aortic valve replacement</subject><subject>Children</subject><subject>Echocardiography</subject><subject>Heart</subject><subject>Heart surgery</subject><subject>Morphology</subject><subject>Patients</subject><subject>pediatric</subject><subject>Pediatrics</subject><subject>Pericardium</subject><subject>Postoperative period</subject><subject>Regurgitation</subject><subject>Stenosis</subject><subject>transesophageal echocardiography</subject><subject>Ventricle</subject><subject>Weaning</subject><issn>1328-8067</issn><issn>1442-200X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp10MtKAzEUBuAgiq2XhS8gATe6GJvbZFJ3ovUCBUVU3IVM5oymTGdq0lF05SP4jD6J0Wk3gtkkJF9-Dj9CO5Qc0rgGMygOqZCKrKA-FYIljJCH1XjmTCWKyKyHNkKYEEJUpsQ66nEu00wq3kc396Z6aSvjsX0y9SMEbMo5eGwaP3cWv8RXwDU0Xx-ftg0zV7h3M3dNjV0df7iq8FAf4WNsTQAcwDsIW2itNFWA7cW-ie7ORrcnF8n46vzy5HicWJ5lJLGptYzRVKaUWSEZJynQlBYslwWnxipWDEHkUpholMozzvKSqyHnRBClgG-i_S535pvnFsJcT12wUFUmztsGzcQwI4qqlES694dOmtbXcTrN0qGSnGdCRHXQKeubEDyUeubd1Pg3TYn-KVrHovVv0dHuLhLbfBpvl3LZbASDDry6Ct7-T9LXo9Mu8hsgNYYe</recordid><startdate>202111</startdate><enddate>202111</enddate><creator>Watanabe, Fumio</creator><creator>Go, Kiyotaka</creator><creator>Kojima, Taiki</creator><general>Blackwell Publishing Ltd</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-7815-7185</orcidid><orcidid>https://orcid.org/0000-0001-7136-9815</orcidid><orcidid>https://orcid.org/0000-0001-9206-4033</orcidid></search><sort><creationdate>202111</creationdate><title>Valvular changes after aortic valve neo‐cuspidization in children: A case series</title><author>Watanabe, Fumio ; Go, Kiyotaka ; Kojima, Taiki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3770-c5cc22156512c462305e151d2b6d31ac82d9e4b64a15688b732bf3893304088e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Aortic valve</topic><topic>aortic valve neo‐cuspidization</topic><topic>aortic valve regurgitation</topic><topic>aortic valve replacement</topic><topic>Children</topic><topic>Echocardiography</topic><topic>Heart</topic><topic>Heart surgery</topic><topic>Morphology</topic><topic>Patients</topic><topic>pediatric</topic><topic>Pediatrics</topic><topic>Pericardium</topic><topic>Postoperative period</topic><topic>Regurgitation</topic><topic>Stenosis</topic><topic>transesophageal echocardiography</topic><topic>Ventricle</topic><topic>Weaning</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Watanabe, Fumio</creatorcontrib><creatorcontrib>Go, Kiyotaka</creatorcontrib><creatorcontrib>Kojima, Taiki</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatrics international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Watanabe, Fumio</au><au>Go, Kiyotaka</au><au>Kojima, Taiki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Valvular changes after aortic valve neo‐cuspidization in children: A case series</atitle><jtitle>Pediatrics international</jtitle><addtitle>Pediatr Int</addtitle><date>2021-11</date><risdate>2021</risdate><volume>63</volume><issue>11</issue><spage>1289</spage><epage>1296</epage><pages>1289-1296</pages><issn>1328-8067</issn><eissn>1442-200X</eissn><abstract>Background
Aortic valve neo‐cuspidization (AVNeo), a procedure wherein the aortic valve is reconstructed utilizing an autologous pericardium, has recently been more commonly performed in children. However, the postoperative morphological changes in the aortic valve of pediatric patients remain unknown. The current study aimed to describe the intraoperative and postoperative findings of aortic regurgitation (AR) and stenosis (AS) after AVNeo in children.
Methods
This case series describes the morphological changes in AR and AS, and their severity, between the perioperative period and 3 months postoperative period after AVNeo in children (<18 years) who underwent AVNeo between April 2016 and March 2020. Data were collected at two measurement points: (i) intraoperative transesophageal echocardiography after weaning from cardiopulmonary bypass (io‐TEE); (ii) postoperative transthoracic echocardiography 3 months after the procedure (po‐TTE).
Results
Seven patients were included in this case series. The number of postoperative AR sites and the ratio of AR jet area to the left ventricular outflow tract area showed a tendency to decrease between io‐TEE and po‐TTE. All AR sites were integrated during the postoperative period. One patient identified developed intraoperative AS, which maintained its severity after AVNeo.
Conclusions
Most cases exhibited spontaneous improvement in AR, while one developed postoperative AS. Further prospective investigation is, therefore, needed to explore surgical outcomes following AVNeo among children.</abstract><cop>Australia</cop><pub>Blackwell Publishing Ltd</pub><pmid>33657683</pmid><doi>10.1111/ped.14680</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-7815-7185</orcidid><orcidid>https://orcid.org/0000-0001-7136-9815</orcidid><orcidid>https://orcid.org/0000-0001-9206-4033</orcidid></addata></record> |
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source | Wiley Online Library Journals Frontfile Complete |
subjects | Aortic valve aortic valve neo‐cuspidization aortic valve regurgitation aortic valve replacement Children Echocardiography Heart Heart surgery Morphology Patients pediatric Pediatrics Pericardium Postoperative period Regurgitation Stenosis transesophageal echocardiography Ventricle Weaning |
title | Valvular changes after aortic valve neo‐cuspidization in children: A case series |
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