Proteogenomics of glioblastoma associates molecular patterns with survival

Glioblastoma (GBM) is the most aggressive form of glioma, with poor prognosis exhibited by most patients, and a median survival time of less than 2 years. We assemble a cohort of 87 GBM patients whose survival ranges from less than 3 months and up to 10 years and perform both high-resolution mass sp...

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Veröffentlicht in:	Cell reports (Cambridge) 2021-03, Vol.34 (9), p.108787-108787, Article 108787
Hauptverfasser:	Yanovich-Arad, Gali, Ofek, Paula, Yeini, Eilam, Mardamshina, Mariya, Danilevsky, Artem, Shomron, Noam, Grossman, Rachel, Satchi-Fainaro, Ronit, Geiger, Tamar
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Brain Neoplasms - genetics Brain Neoplasms - metabolism Brain Neoplasms - mortality Brain Neoplasms - pathology cancer heterogeneity Cluster Analysis Computational Biology Databases, Genetic Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene Regulatory Networks glioblastoma Glioblastoma - genetics Glioblastoma - metabolism Glioblastoma - mortality Glioblastoma - pathology Humans Male mass spectrometry Middle Aged Prognosis Protein Interaction Maps proteogenomics Proteome Proteomics RNA-Seq RNA-sequencing Signal Transduction Single-Cell Analysis Survival Analysis Tandem Mass Spectrometry Time Factors Transcriptome Young Adult
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