How to choose a time zero for patients in external control arms

When a sponsor carries out a single‐arm trial of a novel oncology compound, it may wish to assess the efficacy of the compound via comparison of overall survival to an external control arm, constructed using patients included in some retrospective registry. If efficacy of the novel compound is compa...

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Veröffentlicht in:	Pharmaceutical statistics : the journal of the pharmaceutical industry 2021-07, Vol.20 (4), p.783-792
1. Verfasser:	Backenroth, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemotherapy external control arms Humans oncology Patients real world data Research Design Retrospective Studies
Online-Zugang:	Volltext
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