Diagnostic yield of computed tomography in the evaluation of unilateral vocal fold palsy
There is a paucity of Asian-based data regarding the diagnostic yield of computed tomography imaging in the initial assessment of idiopathic unilateral vocal fold palsy. To investigate the diagnostic yield of computed tomography in idiopathic unilateral vocal fold palsy cases in an Asian tertiary ho...
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| Veröffentlicht in: | Journal of laryngology and otology 2021-03, Vol.135 (3), p.255-258 |
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| creator | Chew, H S Goh, J C G Tham, D Y A |
| description | There is a paucity of Asian-based data regarding the diagnostic yield of computed tomography imaging in the initial assessment of idiopathic unilateral vocal fold palsy.
To investigate the diagnostic yield of computed tomography in idiopathic unilateral vocal fold palsy cases in an Asian tertiary hospital, and to determine the causative pathologies and positive predictive factors.
A retrospective chart review was conducted of patients (between 2010 and 2018) with a clinical diagnosis of idiopathic unilateral vocal fold palsy who underwent contrast-enhanced computed tomography of the neck and chest at Tan Tock Seng Hospital, Singapore.
The overall computed tomography diagnostic yield was 21 per cent, with malignancy accounting for 63.6 per cent of diagnoses. Degree of vocal fold weakness was the only significant predictor of positive computed tomography findings (11.5 per cent in vocal fold paresis vs 29.1 per cent in vocal fold paralysis, p = 0.025). None of the patients with negative computed tomography findings went on to develop disease after a mean follow up of 14.3 months.
Computed tomography is a useful initial investigation for idiopathic unilateral vocal fold palsy, particularly in cases with vocal fold paralysis. |
| doi_str_mv | 10.1017/S0022215121000463 |
| format | Article |
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To investigate the diagnostic yield of computed tomography in idiopathic unilateral vocal fold palsy cases in an Asian tertiary hospital, and to determine the causative pathologies and positive predictive factors.
A retrospective chart review was conducted of patients (between 2010 and 2018) with a clinical diagnosis of idiopathic unilateral vocal fold palsy who underwent contrast-enhanced computed tomography of the neck and chest at Tan Tock Seng Hospital, Singapore.
The overall computed tomography diagnostic yield was 21 per cent, with malignancy accounting for 63.6 per cent of diagnoses. Degree of vocal fold weakness was the only significant predictor of positive computed tomography findings (11.5 per cent in vocal fold paresis vs 29.1 per cent in vocal fold paralysis, p = 0.025). None of the patients with negative computed tomography findings went on to develop disease after a mean follow up of 14.3 months.
Computed tomography is a useful initial investigation for idiopathic unilateral vocal fold palsy, particularly in cases with vocal fold paralysis.</description><identifier>ISSN: 0022-2151</identifier><identifier>EISSN: 1748-5460</identifier><identifier>DOI: 10.1017/S0022215121000463</identifier><identifier>PMID: 33648615</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Adult ; Aneurysms ; Computed tomography ; Cysts ; Disease ; Ethnicity ; Female ; Humans ; Intubation ; Main Articles ; Male ; Malignancy ; Medical diagnosis ; Medical imaging ; Metastasis ; Middle Aged ; Paralysis ; Paresis ; Patients ; Radiography ; Retrospective Studies ; Singapore ; Statistical analysis ; Thoracic surgery ; Thymus gland ; Thyroid gland ; Tomography ; Tomography, X-Ray Computed - statistics & numerical data ; Tuberculosis ; Tumors ; Ultrasonic imaging ; Vocal Cord Paralysis - diagnostic imaging ; Vocal Cords - diagnostic imaging ; Vocal organs ; X-rays</subject><ispartof>Journal of laryngology and otology, 2021-03, Vol.135 (3), p.255-258</ispartof><rights>Copyright © The Author(s), 2021. Published by Cambridge University Press</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c373t-f84afff407f2f2de732032d72c8e96939d327292c0ab5a61e6118710735780aa3</citedby><cites>FETCH-LOGICAL-c373t-f84afff407f2f2de732032d72c8e96939d327292c0ab5a61e6118710735780aa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S0022215121000463/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>164,314,780,784,27924,27925,55628</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33648615$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chew, H S</creatorcontrib><creatorcontrib>Goh, J C G</creatorcontrib><creatorcontrib>Tham, D Y A</creatorcontrib><title>Diagnostic yield of computed tomography in the evaluation of unilateral vocal fold palsy</title><title>Journal of laryngology and otology</title><addtitle>J. Laryngol. Otol</addtitle><description>There is a paucity of Asian-based data regarding the diagnostic yield of computed tomography imaging in the initial assessment of idiopathic unilateral vocal fold palsy.
To investigate the diagnostic yield of computed tomography in idiopathic unilateral vocal fold palsy cases in an Asian tertiary hospital, and to determine the causative pathologies and positive predictive factors.
A retrospective chart review was conducted of patients (between 2010 and 2018) with a clinical diagnosis of idiopathic unilateral vocal fold palsy who underwent contrast-enhanced computed tomography of the neck and chest at Tan Tock Seng Hospital, Singapore.
The overall computed tomography diagnostic yield was 21 per cent, with malignancy accounting for 63.6 per cent of diagnoses. Degree of vocal fold weakness was the only significant predictor of positive computed tomography findings (11.5 per cent in vocal fold paresis vs 29.1 per cent in vocal fold paralysis, p = 0.025). None of the patients with negative computed tomography findings went on to develop disease after a mean follow up of 14.3 months.
Computed tomography is a useful initial investigation for idiopathic unilateral vocal fold palsy, particularly in cases with vocal fold paralysis.</description><subject>Adult</subject><subject>Aneurysms</subject><subject>Computed tomography</subject><subject>Cysts</subject><subject>Disease</subject><subject>Ethnicity</subject><subject>Female</subject><subject>Humans</subject><subject>Intubation</subject><subject>Main Articles</subject><subject>Male</subject><subject>Malignancy</subject><subject>Medical diagnosis</subject><subject>Medical imaging</subject><subject>Metastasis</subject><subject>Middle Aged</subject><subject>Paralysis</subject><subject>Paresis</subject><subject>Patients</subject><subject>Radiography</subject><subject>Retrospective Studies</subject><subject>Singapore</subject><subject>Statistical analysis</subject><subject>Thoracic surgery</subject><subject>Thymus gland</subject><subject>Thyroid gland</subject><subject>Tomography</subject><subject>Tomography, X-Ray Computed - statistics & numerical data</subject><subject>Tuberculosis</subject><subject>Tumors</subject><subject>Ultrasonic imaging</subject><subject>Vocal Cord Paralysis - diagnostic imaging</subject><subject>Vocal Cords - diagnostic imaging</subject><subject>Vocal organs</subject><subject>X-rays</subject><issn>0022-2151</issn><issn>1748-5460</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kE1LxDAQhoMo7rr6A7xIwYuX6iRpmvYo6ycIHlTwVrJtspulbWqSLvTfm7KrguJl5jDPPDO8CJ1iuMSA-dULACEEM0wwACQp3UNTzJMsZkkK-2g6juNxPkFHzq0DgzmQQzShNE2yFLMper_RYtka53UZDVrWVWRUVJqm672sIm8as7SiWw2RbiO_kpHciLoXXpt2BPtW18JLK-poY8pQlQmGTtRuOEYHKnR5susz9HZ3-zp_iJ-e7x_n109xSTn1scoSoZRKgCuiSCU5JUBJxUmZyTzNaV5RwklOShALJlIsU4wzjoFTxjMQgs7QxdbbWfPRS-eLRrtS1rVopeldQZKcJSGUPAvo-S90bXrbhu8KwoCyjOWQBwpvqdIa56xURWd1I-xQYCjG2Is_sYeds525XzSy-t74yjkAdCcVzcLqail_bv-v_QSTMorP</recordid><startdate>202103</startdate><enddate>202103</enddate><creator>Chew, H S</creator><creator>Goh, J C G</creator><creator>Tham, D Y A</creator><general>Cambridge University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0X</scope><scope>7X8</scope></search><sort><creationdate>202103</creationdate><title>Diagnostic yield of computed tomography in the evaluation of unilateral vocal fold palsy</title><author>Chew, H S ; Goh, J C G ; Tham, D Y A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c373t-f84afff407f2f2de732032d72c8e96939d327292c0ab5a61e6118710735780aa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adult</topic><topic>Aneurysms</topic><topic>Computed tomography</topic><topic>Cysts</topic><topic>Disease</topic><topic>Ethnicity</topic><topic>Female</topic><topic>Humans</topic><topic>Intubation</topic><topic>Main Articles</topic><topic>Male</topic><topic>Malignancy</topic><topic>Medical diagnosis</topic><topic>Medical imaging</topic><topic>Metastasis</topic><topic>Middle Aged</topic><topic>Paralysis</topic><topic>Paresis</topic><topic>Patients</topic><topic>Radiography</topic><topic>Retrospective Studies</topic><topic>Singapore</topic><topic>Statistical analysis</topic><topic>Thoracic surgery</topic><topic>Thymus gland</topic><topic>Thyroid gland</topic><topic>Tomography</topic><topic>Tomography, X-Ray Computed - statistics & numerical data</topic><topic>Tuberculosis</topic><topic>Tumors</topic><topic>Ultrasonic imaging</topic><topic>Vocal Cord Paralysis - diagnostic imaging</topic><topic>Vocal Cords - diagnostic imaging</topic><topic>Vocal organs</topic><topic>X-rays</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chew, H S</creatorcontrib><creatorcontrib>Goh, J C G</creatorcontrib><creatorcontrib>Tham, D Y A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of laryngology and otology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chew, H S</au><au>Goh, J C G</au><au>Tham, D Y A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diagnostic yield of computed tomography in the evaluation of unilateral vocal fold palsy</atitle><jtitle>Journal of laryngology and otology</jtitle><addtitle>J. Laryngol. Otol</addtitle><date>2021-03</date><risdate>2021</risdate><volume>135</volume><issue>3</issue><spage>255</spage><epage>258</epage><pages>255-258</pages><issn>0022-2151</issn><eissn>1748-5460</eissn><abstract>There is a paucity of Asian-based data regarding the diagnostic yield of computed tomography imaging in the initial assessment of idiopathic unilateral vocal fold palsy.
To investigate the diagnostic yield of computed tomography in idiopathic unilateral vocal fold palsy cases in an Asian tertiary hospital, and to determine the causative pathologies and positive predictive factors.
A retrospective chart review was conducted of patients (between 2010 and 2018) with a clinical diagnosis of idiopathic unilateral vocal fold palsy who underwent contrast-enhanced computed tomography of the neck and chest at Tan Tock Seng Hospital, Singapore.
The overall computed tomography diagnostic yield was 21 per cent, with malignancy accounting for 63.6 per cent of diagnoses. Degree of vocal fold weakness was the only significant predictor of positive computed tomography findings (11.5 per cent in vocal fold paresis vs 29.1 per cent in vocal fold paralysis, p = 0.025). None of the patients with negative computed tomography findings went on to develop disease after a mean follow up of 14.3 months.
Computed tomography is a useful initial investigation for idiopathic unilateral vocal fold palsy, particularly in cases with vocal fold paralysis.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>33648615</pmid><doi>10.1017/S0022215121000463</doi><tpages>4</tpages></addata></record> |
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| subjects | Adult Aneurysms Computed tomography Cysts Disease Ethnicity Female Humans Intubation Main Articles Male Malignancy Medical diagnosis Medical imaging Metastasis Middle Aged Paralysis Paresis Patients Radiography Retrospective Studies Singapore Statistical analysis Thoracic surgery Thymus gland Thyroid gland Tomography Tomography, X-Ray Computed - statistics & numerical data Tuberculosis Tumors Ultrasonic imaging Vocal Cord Paralysis - diagnostic imaging Vocal Cords - diagnostic imaging Vocal organs X-rays |
| title | Diagnostic yield of computed tomography in the evaluation of unilateral vocal fold palsy |
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