Determination of Fentanyl, Alpha-Methylfentanyl, Beta-Hydroxyfentanyl and the Metabolite Norfentanyl in Rat Urine by LC–MS-MS

Abstract Fentanyl and its analogs are potent synthetic opioids with a high potential for abuse and dependence. They have become major contributors to opioid deaths. This study aimed to determine whether the metabolites of fentanyl, alpha-methylfentanyl and beta-hydroxyfentanyl, excreted in the urine...

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Veröffentlicht in:	Journal of analytical toxicology 2022-04, Vol.46 (4), p.421-431
Hauptverfasser:	Li, Lu, Yu, Xuejiao, Lyu, Lihong, Duan, Hongbin, Chen, Yao, Bian, Jing, Xu, Zhiru, Liu, Li, Zhang, Yurong
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics, Opioid - analysis Animals Chromatography, Liquid - methods Fentanyl - analogs & derivatives Rats Rats, Sprague-Dawley Tandem Mass Spectrometry
Online-Zugang:	Volltext
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