Advances in machine learning for directed evolution

Machine learning (ML) can expedite directed evolution by allowing researchers to move expensive experimental screens in silico. Gathering sequence-function data for training ML models, however, can still be costly. In contrast, raw protein sequence data is widely available. Recent advances in ML app...

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Veröffentlicht in:	Current opinion in structural biology 2021-08, Vol.69, p.11-18
Hauptverfasser:	Wittmann, Bruce J, Johnston, Kadina E, Wu, Zachary, Arnold, Frances H
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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