Transmucosal Delivery of Self-Assembling Photosensitizer–Nitazoxanide Nanocomplexes with Fluorinated Chitosan for Instillation-Based Photodynamic Therapy of Orthotopic Bladder Tumors

Theoretically, on account of improved local bioavailability of photosensitizers and attenuated systemic phototoxicity, intravesical instillation-based photodynamic therapy (PDT) for bladder cancer (BCa) would demonstrate significant advantages in comparison with the intravenous route. Actually, the...

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Veröffentlicht in:	ACS biomaterials science & engineering 2021-04, Vol.7 (4), p.1485-1495
Hauptverfasser:	Wang, Shupeng, Jin, Shaohua, Li, Guangzhi, Xu, Ming, Deng, Dashi, Xiao, Zhisheng, Sun, Haiyan, Zhang, Shaohua, Zhang, Enpu, Xie, Lejing, Li, Guo, Dai, Yizhi, Liu, Zhuang, Shu, Qinghai, Wu, Song
Format:	Artikel
Sprache:	eng
Schlagworte:	Chitosan - therapeutic use Controlled Release and Delivery Systems Humans Nitro Compounds Photochemotherapy Photosensitizing Agents - therapeutic use Thiazoles Urinary Bladder Neoplasms - drug therapy
Online-Zugang:	Volltext
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