Collapsin response mediator protein 5 (CRMP5) modulates susceptibility to chronic social defeat stress in mice

Collapsin response mediator protein 5 (CRMP5), a member of the CRMP family, is expressed in the brain, particularly in the hippocampus, an area of the brain that can modulate stress responses. Social stress has a well-known detrimental effect on health and can lead to depression, but not all individ...

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Veröffentlicht in:	Molecular neurobiology 2021-07, Vol.58 (7), p.3175-3186
Hauptverfasser:	Lin, Yu-Fen, Chen, Kao Chin, Yang, Yen Kuang, Hsiao, Ya-Hsin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Avoidance behavior Behavior Biomedical and Life Sciences Biomedicine Cell Biology Corticosterone Gene Knockdown Techniques - methods HEK293 Cells Hippocampus Hippocampus - metabolism Humans Hydrolases - antagonists & inhibitors Hydrolases - biosynthesis Hydrolases - genetics Male Mediator protein Medical schools Medicine Mental depression Mice Mice, Inbred C57BL Microtubule-Associated Proteins - antagonists & inhibitors Microtubule-Associated Proteins - biosynthesis Microtubule-Associated Proteins - genetics Neurobiology Neurology Neurosciences Proteins Social behavior Social Defeat Social interaction Social interactions Stress Stress, Psychological - genetics Stress, Psychological - metabolism Stress, Psychological - psychology
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