Delay to surgery after neoadjuvant chemotherapy in head and neck squamous cell carcinoma affects oncologic outcomes

Background Neoadjuvant chemotherapy (NAC) is used in head and neck squamous cell carcinoma (HNSCC) for downstaging advanced disease and decreasing distant metastasis (DM). To the authors' knowledge, no study has specifically examined the impact of a delayed time to surgery (TTS) after NAC on on...

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Veröffentlicht in:	Cancer 2021-06, Vol.127 (12), p.1984-1992
Hauptverfasser:	Kiong, Kimberley L., Yao, Christopher M. K. L., Lin, Fang‐Yu, Bell, Diana, Ferrarotto, Renata, Weber, Randal S., Lewis, Carol M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Benchmarks Cancer Chemotherapy Confidence intervals Disease-Free Survival Head & neck cancer head and neck neoplasms Head and Neck Neoplasms - drug therapy Head and Neck Neoplasms - surgery Humans Metastases Multivariate analysis Neoadjuvant Therapy Neoplasm Recurrence, Local - pathology Oncology Patients Regression analysis Retrospective Studies Squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck - drug therapy Squamous Cell Carcinoma of Head and Neck - surgery Statistical analysis Surgery Survival Weight loss
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