Exosomal miR-128-3p Promotes Epithelial-to-Mesenchymal Transition in Colorectal Cancer Cells by Targeting FOXO4 via TGF-beta/SMAD and JAK/STAT3 Signaling

Epithelial-to-mesenchymal transition (EMT) is a key process that occurs during tumor metastasis, affecting a variety of malignancies including colorectal cancer (CRC). Exosomes mediate cell-cell communication by transporting cell-derived proteins and nucleic acids, including microRNAs (miRNAs). Exos...

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Veröffentlicht in:	Frontiers in cell and developmental biology 2021-02, Vol.9, p.568738, Article 568738
Hauptverfasser:	Bai, Jian, Zhang, Xue, Shi, Dongdong, Xiang, Zhenxian, Wang, Shuyi, Yang, Chaogang, Liu, Qing, Huang, Sihao, Fang, Yan, Zhang, Weisong, Song, Jialin, Xiong, Bin
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell and Developmental Biology Cell Biology Developmental Biology Life Sciences & Biomedicine Science & Technology
Online-Zugang:	Volltext
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