The effects of recombinant klotho in cisplatin‐induced ovarian failure in mice

Aim To investigate whether recombinant klotho given concomitantly with cisplatin is effective in preventing cisplatin‐induced ovarian damage. Methods Thirty‐two adult female mice were divided into four groups. Saline was given to the first group, cisplatin to the second group, recombinant mouse klot...

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Veröffentlicht in:	The journal of obstetrics and gynaecology research 2021-05, Vol.47 (5), p.1817-1824
Hauptverfasser:	Biyik, Ismail, Ozatik, Fikriye Yasemin, Albayrak, Mustafa, Ozatik, Orhan, Teksen, Yasemin, Ari, Neziha Senem, Soysal, Cenk
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants anti‐mullerian hormone Catalase Chemotherapy Cisplatin cisplatin‐induced ovarian injury Corpus luteum Degeneration Edema Enzyme-linked immunosorbent assay Glutathione peroxidase Glutathione reductase klotho Klotho protein ovarian reserve Ovaries Oxidative stress Reproductive status Superoxide dismutase
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