High-resolution HLA typing by long reads from the R10.3 Oxford nanopore flow cells

Nanopore sequencing has been investigated as a rapid and cost-efficient option for HLA typing in recent years. Despite the lower raw read accuracy, encouraging typing accuracy has been reported, and long reads from the platform offer additional benefits of the improved phasing of distant variants. T...

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Veröffentlicht in:	Human immunology 2021-04, Vol.82 (4), p.288-295
Hauptverfasser:	Liu, Chang, Yang, Xiao, Duffy, Brian F., Hoisington-Lopez, Jessica, Crosby, MariaLynn, Porche-Sorbet, Rhonda, Saito, Katsuyuki, Berry, Rick, Swamidass, Victoria, Mitra, Robi D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Human leukocyte antigen Nanopore sequencing Next-generation sequencing R10.3 flow cells
Online-Zugang:	Volltext
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