Pharmacogenetics of sulfonylurea: Presence of CYP2C92, CYP2C93 and a novel allele, CYP2C961, in Type 2 diabetes patients under sulfonylurea therapy

CYP2C9 is an important member of the cytochrome P450 gene family involved in the metabolism of 15% of the drugs including an oral antidiabetic agent sulfonylurea. This study aims to investigate the frequency of CYP2C9*2 and CYP2C9*3 alleles of the gene in the sulfonylurea treated diabetic subjects i...

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Veröffentlicht in:Pakistan journal of pharmaceutical sciences 2020-07, Vol.33 (4(Supplementary)), p.1771-1777
Hauptverfasser: Muhammad, Sumaira Deen, Khan, Hazar, Hussain, Mushtaq, Zeb, Tehseen Fatima, Kumar, Darshan, Rahi, Rahimullah, Asif, Mahayrookh, Balooch, Akhter Ali
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Sprache:eng
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