Structural Dynamic Heterogeneity of Polyubiquitin Subunits Affects Phosphorylation Susceptibility

Polyubiquitin is a multifunctional protein tag formed by the covalent conjugation of ubiquitin molecules. Due to the high rigidity of the ubiquitin fold, the ubiquitin moieties in a polyubiquitin chain appear to be structurally equivalent to each other. It is therefore unclear how a specific ubiquit...

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Veröffentlicht in:	Biochemistry (Easton) 2021-03, Vol.60 (8), p.573-583
Hauptverfasser:	Morimoto, Daichi, Walinda, Erik, Takashima, Shingo, Nishizawa, Mayu, Iwai, Kazuhiro, Shirakawa, Masahiro, Sugase, Kenji
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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