Enhanced in vitro anticancer activity of yeast expressed recombinant glucose oxidase versus commercial enzyme

Cancer treatments continue to have many disadvantages. Reactive oxygen species, such as H 2 O 2 , in high concentrations, can cause cytotoxicity to cells, being even greater in cancer cells. One of the H 2 O 2 -producing enzymes is glucose oxidase; its application in cancer treatment should be explo...

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Veröffentlicht in:	Applied microbiology and biotechnology 2021-03, Vol.105 (6), p.2377-2384
Hauptverfasser:	Martínez-Mora, Evelyn, González-González, María Del Rosario, Zarate, Xristo, Carranza-Rosales, Pilar, Ramírez-Cabrera, Mónica A., Balderas-Rentería, Isaías, Arredondo-Espinoza, Eder
Format:	Artikel
Sprache:	eng
Schlagworte:	Anion exchange Anion exchanging Anticancer properties Antitumor activity Applied Genetics and Molecular Biotechnology Biomedical and Life Sciences Biotechnology Cancer Cancer therapies Care and treatment Comparative analysis Cytotoxicity Enzymes Gel electrophoresis Gene expression Genetic aspects Glucose Glucose Oxidase Health aspects Hydrogen Peroxide Identification and classification Life Sciences Microbial Genetics and Genomics Microbiology Molecular weight Optimization Oxidoreductases Pichia - genetics Pichia pastoris Post-translation Protein purification Proteins Purification Reactive oxygen species Recombinant proteins Recombinant Proteins - genetics Saccharomyces cerevisiae - genetics Saccharomycetales Sodium lauryl sulfate Toxicity Varieties Yeast Yeast fungi Yeasts
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