Functional Skeletal Muscle Regeneration with Thermally Drawn Porous Fibers and Reprogrammed Muscle Progenitors for Volumetric Muscle Injury

Skeletal muscle has an inherent capacity for spontaneous regeneration. However, recovery after severe injuries such as volumetric muscle loss (VML) is limited. There is therefore a need to develop interventions to induce functional skeletal muscle restoration. One suggested approach includes tissue‐...

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Veröffentlicht in:	Advanced materials (Weinheim) 2021-04, Vol.33 (14), p.e2007946-n/a
Hauptverfasser:	Jin, Yoonhee, Shahriari, Dena, Jeon, Eun Je, Park, Seongjun, Choi, Yi Sun, Back, Jonghyeok, Lee, Hyungsuk, Anikeeva, Polina, Cho, Seung‐Woo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bioengineering Cell Differentiation Cells (biology) Construction engineering direct reprogramming Extracellular Matrix - chemistry Extracellular Matrix - metabolism Injury prevention Materials science Mice Microchannels Muscle Development Muscle, Skeletal - injuries Muscles Musculoskeletal system Porosity Recovery Regeneration Scaffolds skeletal muscle regeneration Stem Cells - cytology Temperature thermal fiber drawing Tissue engineering Tissue Engineering - methods Tissue Scaffolds - chemistry volumetric muscle loss
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