Studies on apoptosis induced by B-norcholesteryl benzimidazole compounds in HeLa cells

[Display omitted] •B-norcholesteryl Benzimidazole Compounds can change cervical cancer HeLa cell morphology and inhibit its proliferation, invasion and metastasis.•Furthermore, the compound can induce apoptosis of HeLa cells.•The compounds block HeLa cell proliferation in the early stage of DNA synt...

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Veröffentlicht in:	Steroids 2021-04, Vol.168, p.108802, Article 108802
Hauptverfasser:	Huang, Xiaotong, Wu, Yulan, Huang, Yanmin, Liu, Qinzhou, Chen, Hualong, Dai, Feng, Liang, Fengyan, Gan, Chunfang
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Apoptosis Apoptosis - drug effects B-norcholesteryl benzimidazole compounds Benzimidazoles - chemistry Benzimidazoles - pharmacology Cell cycle Cell Cycle - drug effects Cell Movement - drug effects Cell Proliferation - drug effects Dose-Response Relationship, Drug HeLa HeLa Cells Humans Membrane Potential, Mitochondrial - drug effects Mitochondrial membrane potential
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