Tet2 Inactivation Enhances the Antitumor Activity of Tumor-Infiltrating Lymphocytes

Inactivation of tumor-infiltrating lymphocytes (TIL) is one of the mechanisms mitigating antitumor immunity during tumor onset and progression. Epigenetic abnormalities are regarded as a major culprit contributing to the dysfunction of TILs within tumor microenvironments. In this study, we used a mu...

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Veröffentlicht in:Cancer research (Chicago, Ill.) Ill.), 2021-04, Vol.81 (8), p.1965-1976
Hauptverfasser: Lee, Minjung, Li, Jianfang, Li, Jia, Fang, Shaohai, Zhang, Joanna, Vo, Anh Tran Tram, Han, Wei, Zeng, Hongxiang, Isgandarova, Sevinj, Martinez-Moczygemba, Margarita, Zhou, Yubin, Sun, Deqiang, Huang, Yun
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Sprache:eng
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