Phytochemicals in thyroid cancer: analysis of the preclinical studies

Purpose In the search for novel effective compounds to use in thyroid cancer (TC) unresponsive to current treatment, attention has recently focused on plant-derived compounds with anticancer activity. In this review, we discuss the preclinical studies demonstrating phytochemical activity against thy...

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Veröffentlicht in:Endocrine 2021-07, Vol.73 (1), p.8-15
Hauptverfasser: Bulotta, Stefania, Capriglione, Francesca, Celano, Marilena, Pecce, Valeria, Russo, Diego, Maggisano, Valentina
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container_end_page 15
container_issue 1
container_start_page 8
container_title Endocrine
container_volume 73
creator Bulotta, Stefania
Capriglione, Francesca
Celano, Marilena
Pecce, Valeria
Russo, Diego
Maggisano, Valentina
description Purpose In the search for novel effective compounds to use in thyroid cancer (TC) unresponsive to current treatment, attention has recently focused on plant-derived compounds with anticancer activity. In this review, we discuss the preclinical studies demonstrating phytochemical activity against thyroid cancer cells. Results/Conclusions In particular, we describe their antiproliferative properties or ability to re-induce iodine retention, thus supporting their potential use as single agents or adjuvants in radioiodine-resistant thyroid cancer treatment.
doi_str_mv 10.1007/s12020-021-02651-y
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subjects Adjuvants
Antitumor activity
Diabetes
Endocrinology
Humanities and Social Sciences
Internal Medicine
Iodine
Medicine
Medicine & Public Health
multidisciplinary
Phytochemicals
Plants
Review
Science
Thyroid cancer
title Phytochemicals in thyroid cancer: analysis of the preclinical studies
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