A Real-Time NMR Method for Measurement of In Vitro Aggregation Kinetics Of Degarelix Drug Products

Degarelix is a gonadotropin-releasing hormone (GnRH) receptor antagonist. Upon contact with physiological fluid, degarelix undergoes quick gelation and forms a depot at the site of injection providing sustained release. The molecular gelling kinetics is a critical physiochemical quality attribute of...

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Veröffentlicht in:	AAPS PharmSciTech 2021-02, Vol.22 (2), p.73-73, Article 73
Hauptverfasser:	Patil, Sharadrao M., Qin, Bin, Wang, Yan, Ahmed, Snober, Yilmaz, Huzeyfe, Jiang, Xiaohui, Keire, David A., Chen, Kang
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedical and Life Sciences Biomedicine Biotechnology Brief/Technical Note Drug Development Humans Kinetics Magnetic Resonance Spectroscopy - methods Male Oligopeptides - chemistry Pharmacology/Toxicology Pharmacy Prostatic Neoplasms - drug therapy
Online-Zugang:	Volltext
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