Targeting KRAS in Colorectal Cancer

Purpose of Review Mutations in kirsten rat sarcoma viral oncogene homolog (KRAS) are the most frequently observed genomic alterations in human cancers. No KRAS targeting therapy has been approved despite more than three decades of efforts. Encouraging progress has been made in targeting KRAS G12C wi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Current oncology reports 2021-03, Vol.23 (3), p.28-28, Article 28
Hauptverfasser:	Wang, Chongkai, Fakih, Marwan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - therapeutic use Antitumor activity Carcinoma, Non-Small-Cell Lung - drug therapy Clinical trials Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - drug therapy Dose-Response Relationship, Drug Evolving Therapies (RM Bukowski Humans K-Ras protein Lung cancer Lung Neoplasms - drug therapy Medicine Medicine & Public Health Molecular Targeted Therapy - methods Mutation Non-small cell lung carcinoma Oncology Proto-Oncogene Proteins p21(ras) - drug effects Sarcoma Section Editor Small cell lung carcinoma Solid tumors Topical Collection on Evolving Therapies Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!