Systolic reserve maintains left ventricular-vascular coupling when challenged by adverse breathing mechanics and hypertension in healthy adults

Augmented negative intrathoracic pressures (nITP) and dynamic hyperinflation (DH) are adverse breathing mechanics (ABM) associated with chronic obstructive pulmonary disease (COPD) that attenuate left ventricular (LV) preload and augment afterload. In COPD, hypertension (elevated systemic arterial l...

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Veröffentlicht in:	Journal of applied physiology (1985) 2021-04, Vol.130 (4), p.1171-1182
Hauptverfasser:	Wright, S P, Cheyne, W S, Gelinas, J C, Harper, M I, Sasso, J P, Eves, N D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Chronic obstructive pulmonary disease Coupling Echocardiography Heart Hypertension Ischemia Lung diseases Mechanics (physics) Obstructive lung disease Respiration Stroke Stroke volume Ventricle
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