Role of 5-HT1A and 5-HT2C receptors of the dorsal periaqueductal gray in the anxiety- and panic-modulating effects of antidepressants in rats

•dPAG 5-HT1A receptors are recruited for the panicolytic effect of chronic imipramine.•Chronic fluoxetine or imipramine does not change 5-HT1A receptor levels in the dPAG.•dPAG 5-HT2C receptors does not mediate the acute anxiogenic effect of antidepressants. Antidepressant drugs are first-line treat...

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Veröffentlicht in:	Behavioural brain research 2021-04, Vol.404, p.113159-113159, Article 113159
Hauptverfasser:	Vilela-Costa, Heloisa H., Maraschin, Jhonatan Christian, Casarotto, Plinio C., Sant’Ana, Ana Beatriz, de Bortoli, Valquiria C., Vicente, Maria Adrielle, Campos, Alline Cristina, Guimarães, Francisco S., Zangrossi, Helio
Format:	Artikel
Sprache:	eng
Schlagworte:	Anxiety Dorsal periaqueductal gray Fluoxetine Imipramine Panic Serotonin
Online-Zugang:	Volltext
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