Rapid tolerance to behavioral effects of ethanol in rats: Prevention by R-(−)-ketamine

R-(−)-ketamine has emerged as a potentially improved medication over that of the (S)-isomer (marketed as Spravato for depression). Recent data have suggested (R)-ketamine could have value in the treatment of substance use disorder. The present set of experiments was undertaken to examine whether (R)...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 2021-04, Vol.203, p.173152, Article 173152
Hauptverfasser:	Shafique, Hana, Witkin, Jeffrey M., Smith, Jodi L., Kaniecki, Kyle, Sporn, Jonathan, Holuj, Malgorzata, Krawczyk, Martyna, Kuziak, Agata, Popik, Piotr
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcoholism - drug therapy Animals Behavior Behavior, Animal - drug effects Ethanol Ethanol - administration & dosage Hand Strength Isomerism Ketamine - administration & dosage Ketamine - chemistry Male Motor Activity - drug effects R-ketamine Rats Rats, Sprague-Dawley Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors Tolerance
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!