One-pot enzymatic synthesis of 2-deoxy-scyllo-inosose from d-glucose and polyphosphate

2-Deoxy-scyllo-inosose (2DOI, [2S,3R,4S,5R]-2,3,4,5-tetrahydroxycyclohexan-1-one) is a biosynthetic intermediate of 2-deoxystreptamine-containing aminoglycoside antibiotics, including butirosin, kanamycin, and neomycin. In producer microorganisms, 2DOI is constructed from d-glucose 6-phosphate (G6P)...

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Veröffentlicht in:Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2021-01, Vol.85 (1), p.108-114
Hauptverfasser: Kudo, Fumitaka, Mori, Ayaka, Koide, Mai, Yajima, Ryo, Takeishi, Ryohei, Miyanaga, Akimasa, Eguchi, Tadashi
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Sprache:eng
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