One-pot enzymatic synthesis of 2-deoxy-scyllo-inosose from d-glucose and polyphosphate
2-Deoxy-scyllo-inosose (2DOI, [2S,3R,4S,5R]-2,3,4,5-tetrahydroxycyclohexan-1-one) is a biosynthetic intermediate of 2-deoxystreptamine-containing aminoglycoside antibiotics, including butirosin, kanamycin, and neomycin. In producer microorganisms, 2DOI is constructed from d-glucose 6-phosphate (G6P)...
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Veröffentlicht in: | Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2021-01, Vol.85 (1), p.108-114 |
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Format: | Artikel |
Sprache: | eng |
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