Multiple vertebral compression fractures in a human immunodeficiency virus-positive patient with glucocorticoid-induced Cushing syndrome treated with percutaneous vertebroplasty: a case report
The authors present a rare case of multiple vertebral compression fractures in a young female with iatrogenic glucocorticoid-induced Cushing syndrome and concomitant human immunodeficiency virus (HIV) infection. Both long-term steroid use and HIV infection may lead to osteopenia or even osteoporosis...
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Veröffentlicht in: | Osteoporosis international 2021-06, Vol.32 (6), p.1233-1237 |
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creator | Hsu, H.-E. Hsu, Y.-P. Yu, C.-H. |
description | The authors present a rare case of multiple vertebral compression fractures in a young female with iatrogenic glucocorticoid-induced Cushing syndrome and concomitant human immunodeficiency virus (HIV) infection. Both long-term steroid use and HIV infection may lead to osteopenia or even osteoporosis. Multiple vertebral fractures in young patients are very uncommon and should alert the examiner to investigate any underlying cause. Treatment choices include pharmacological agents such as bisphosphonates or parathyroid hormone and even surgical interventions such as percutaneous vertebroplasty. |
doi_str_mv | 10.1007/s00198-021-05880-z |
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Both long-term steroid use and HIV infection may lead to osteopenia or even osteoporosis. Multiple vertebral fractures in young patients are very uncommon and should alert the examiner to investigate any underlying cause. Treatment choices include pharmacological agents such as bisphosphonates or parathyroid hormone and even surgical interventions such as percutaneous vertebroplasty.</description><subject>Adrenocorticotropic hormone</subject><subject>Bisphosphonates</subject><subject>Bone surgery</subject><subject>Case Report</subject><subject>Case reports</subject><subject>Compression</subject><subject>Cushing syndrome</subject><subject>Endocrinology</subject><subject>Fractures</subject><subject>Glucocorticoids</subject><subject>HIV</subject><subject>Human immunodeficiency virus</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Nervous system diseases</subject><subject>Orthopedics</subject><subject>Osteopenia</subject><subject>Osteoporosis</subject><subject>Parathyroid</subject><subject>Parathyroid hormone</subject><subject>Pituitary</subject><subject>Rheumatology</subject><subject>Vertebrae</subject><issn>0937-941X</issn><issn>1433-2965</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNp9kc2KFDEUhYMoTs_oC7iQgBs30aSSdFXcSaOOMOJGwV1IpW51Z6hKyvy09Dydj2acmlFwIVmE5H7n3AMHoWeMvmKUtq8TpUx1hDaMUNl1lNw8QBsmOCeN2sqHaEMVb4kS7NsZOk_pmlaRUu1jdMa5bKVidIN-fipTdssE-AgxQx_NhG2YlwgpueDxGI3Npb6w89jgQ5mNx26eiw8DjM468PaEjy6WRJaQXHZHwIvJ9T_jHy4f8H4qNtgQs7PBDcT5oVgY8K6kg_N7nE5-iGEGnCOYXAe3ogWiLdl4CCXdJwvLZFI-vakxrEmAIyzV9Ql6NJopwdO7-wJ9ff_uy-6SXH3-8HH39opY3spM7FbVMzZUqbFTHWtGIeRoe66EZNbY0QJQ2gPdKk75wKiiTIIQtFNDz6HlF-jl6rvE8L1Aynp2ycI0rSF1IzrVSMFbVdEX_6DXoURf0-lGNh1not3ySjUrZWNIKcKol-hmE0-aUf27X732q2u_-rZffVNFz--sSz_D8EdyX2gF-AqkOvJ7iH93_8f2F14-t44</recordid><startdate>20210601</startdate><enddate>20210601</enddate><creator>Hsu, H.-E.</creator><creator>Hsu, Y.-P.</creator><creator>Yu, C.-H.</creator><general>Springer London</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-5608-1290</orcidid></search><sort><creationdate>20210601</creationdate><title>Multiple vertebral compression fractures in a human immunodeficiency virus-positive patient with glucocorticoid-induced Cushing syndrome treated with percutaneous vertebroplasty: a case report</title><author>Hsu, H.-E. ; 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Both long-term steroid use and HIV infection may lead to osteopenia or even osteoporosis. Multiple vertebral fractures in young patients are very uncommon and should alert the examiner to investigate any underlying cause. Treatment choices include pharmacological agents such as bisphosphonates or parathyroid hormone and even surgical interventions such as percutaneous vertebroplasty.</abstract><cop>London</cop><pub>Springer London</pub><pmid>33575910</pmid><doi>10.1007/s00198-021-05880-z</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0001-5608-1290</orcidid></addata></record> |
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subjects | Adrenocorticotropic hormone Bisphosphonates Bone surgery Case Report Case reports Compression Cushing syndrome Endocrinology Fractures Glucocorticoids HIV Human immunodeficiency virus Medicine Medicine & Public Health Nervous system diseases Orthopedics Osteopenia Osteoporosis Parathyroid Parathyroid hormone Pituitary Rheumatology Vertebrae |
title | Multiple vertebral compression fractures in a human immunodeficiency virus-positive patient with glucocorticoid-induced Cushing syndrome treated with percutaneous vertebroplasty: a case report |
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