Time varied illumination laser speckle contrast imaging

Laser speckle contrast imaging is a technique to determine blood flow rate with a limitation of low dynamic range. In this Letter, we introduce a varied illumination speckle contrast imaging method. It utilizes varying illumination during exposure to customize the correlation time (flow rate) to spe...

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Veröffentlicht in:Optics letters 2021-02, Vol.46 (4), p.713
Hauptverfasser: Siket, Máté, Jánoki, Imre, Demeter, Kornél, Szabó, Miklós, Földesy, Péter
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creator Siket, Máté
Jánoki, Imre
Demeter, Kornél
Szabó, Miklós
Földesy, Péter
description Laser speckle contrast imaging is a technique to determine blood flow rate with a limitation of low dynamic range. In this Letter, we introduce a varied illumination speckle contrast imaging method. It utilizes varying illumination during exposure to customize the correlation time (flow rate) to speckle contrast relation. The method can cover an order of magnitude larger range flow rate in a single exposure compared to constant illumination methods. The proposed method enables high dynamic range flow rate imaging, which is advantageous in studying larger vessels and small arteries. We demonstrate the theory by simulations and ex vivo and in vivo measurements.
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source MEDLINE; Optica Publishing Group Journals
subjects Animals
Arteries
Blood flow
Blood vessels
Dynamic range
Flow velocity
Illumination
Imaging
Laser Speckle Contrast Imaging
Lighting - methods
Time Factors
title Time varied illumination laser speckle contrast imaging
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