Exosomal microRNAs in the development of essential hypertension and its potential as biomarkers

MicroRNAs (miRNAs) are small regulatory molecules that are involved in posttranscriptional modifications. These noncoding RNAs are usually ferried by extracellular carriers such as exosomes or other protein and lipid carriers inside a range of body fluids including plasma and urine. Due to their abi...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2021-04, Vol.320 (4), p.H1486-H1497
Hauptverfasser:	Tan, Paulina Pei Suu, Hall, Deborah, Chilian, William M, Chia, Yook Chin, Mohd Zain, Shamsul, Lim, Hooi Min, Kumar, Devaraj Navin, Ching, Siew Mooi, Low, Teck Yew, Md Noh, Mohd Fairulnizal, Pung, Yuh-Fen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers Biomarkers - metabolism Blood Pressure Body fluids Cellular Microenvironment Essential Hypertension - genetics Essential Hypertension - metabolism Essential Hypertension - physiopathology Exosomes Exosomes - genetics Exosomes - metabolism Gene Expression Regulation Humans Hypertension Inflammation Mediators - metabolism Lipids Microenvironments MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism miRNA Oxidative Stress Post-transcription Renin-Angiotensin System Signal Transduction
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