Role of Wnt signaling pathways in type 2 diabetes mellitus

Type 2 diabetes mellitus (T2DM) has become a major global public health issue in the twenty-first century and its incidence has increased each year. Wnt signaling pathways are a set of multi-downstream signaling pathways activated by the binding of Wnt ligands to membrane protein receptors. Wnt sign...

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Veröffentlicht in:	Molecular and cellular biochemistry 2021-05, Vol.476 (5), p.2219-2232
Hauptverfasser:	Chen, Jing, Ning, Chong, Mu, Jingjing, Li, Dongnan, Ma, Yan, Meng, Xianjun
Format:	Artikel
Sprache:	eng
Schlagworte:	Beta cells Biochemistry Biomedical and Life Sciences c-Jun protein Calcineurin Cardiology Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Genetic polymorphisms Glucose tolerance Health aspects Immunological tolerance Inflammation Inflammatory response Insulin Insulin resistance JNK protein Kinases Life Sciences Lymphocytes Medical Biochemistry Medical research Medicine, Experimental Membrane proteins NF-AT protein Oncology Pancreas Physiological aspects Protein binding Proteins Public health Regeneration Signal transduction Signaling T cells Transcription factors Type 2 diabetes Wnt protein β-Catenin
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