Sorted B cell transcriptomes point towards actively regulated B cell responses during ongoing chronic hepatitis B infections

•Four clinical phases describe the natural course of a chronic hepatitis B (CHB) infection.•The immune cells that govern these clinical disease transitions remain unknown.•We performed RNA sequencing on B cells of CHB patients and healthy controls.•We found distinct gene expression profiles between...

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Veröffentlicht in:	Cellular immunology 2021-04, Vol.362, p.104283-104283, Article 104283
Hauptverfasser:	Van Hees, Stijn, Cuypers, Bart, Bourgeois, Stefan, Groothuismink, Zwier M.A., Meysman, Pieter, Van der Vlies, Pieter, de Knegt, Rob, Vonghia, Luisa, Michielsen, Peter, Francque, Sven, Laukens, Kris, Boonstra, Andre, Vanwolleghem, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation B cells HBeAg seroconversion Hepatitis B Intrahepatic RNA sequencing
Online-Zugang:	Volltext
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