New challenges, new opportunities: Next generation sequencing and its place in the advancement of HLA typing

The Human Leukocyte Antigen (HLA) system has a critical role in immunorecognition, transplantation, and disease association. Early typing techniques provided the foundation for genotyping methods that revealed HLA as one of the most complex, polymorphic regions of the human genome. Next Generation S...

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Veröffentlicht in:	Human immunology 2021-07, Vol.82 (7), p.478-487
Hauptverfasser:	Bravo-Egana, Valia, Sanders, Holly, Chitnis, Nilesh
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Genetic Association Studies Genomics - methods Genotype Genotyping Techniques High-Throughput Nucleotide Sequencing Histocompatibility Testing - methods HLA Antigens - genetics HLA typing Humans Next generation sequencing NGS Transplantation Immunology
Online-Zugang:	Volltext
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