Intermittent fasting promotes anxiolytic-like effects unrelated to synaptic mitochondrial function and BDNF support

•Chronic intermittent fasting exerts anxiolytic-like effects without affecting spontaneous exploratory activity.•Reduced anxiety-like behavior was not associated with improvements in mitochondrial parameters or neurotrophic proteins.•We highlight the necessity to explore different mechanisms promoti...

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Veröffentlicht in:	Behavioural brain research 2021-04, Vol.404, p.113163-113163, Article 113163
Hauptverfasser:	Carteri, Randhall B, Menegassi, Lizia Nardi, Feldmann, Marceli, Kopczynski, Afonso, Rodolphi, Marcelo Salimen, Strogulski, Nathan Ryzewski, Almeida, Amanda Staldoni, Marques, Daniela Melo, Porciúncula, Lisiane O., Portela, Luis Valmor
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anxiety Anxiety - etiology Anxiety - metabolism Anxiety - physiopathology Blood Glucose - analysis Blotting, Western Brain - metabolism Brain - physiology Brain-Derived Neurotrophic Factor - metabolism Brain-Derived Neurotrophic Factor - physiology Elevated Plus Maze Test Fasting - adverse effects Fasting - metabolism Fasting - psychology Hydrogen Peroxide - metabolism Ketones - blood Male Membrane Potential, Mitochondrial Mice Mice, Inbred C57BL Mitochondria Mitochondria - metabolism Mitochondria - physiology Neurotrophic factors Nutritional intervention Open Field Test Oxygen Consumption Synapses - metabolism Synapses - physiology Synaptosomes - metabolism Synaptosomes - physiology
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