Apolipoprotein A5 controls fructose-induced metabolic dysregulation in mice

Western dietary habits are partially characterized by increased uptake of fructose, which contributes to metabolic dysregulation and associated liver diseases. For example, a diet enriched with fructose drives insulin resistance and non-alcoholic fatty liver disease (NAFLD). The molecular hubs that...

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Veröffentlicht in:	Nutrition, metabolism, and cardiovascular diseases metabolism, and cardiovascular diseases, 2021-03, Vol.31 (3), p.972-978
Hauptverfasser:	Ress, Claudia, Dobner, Jochen, Rufinatscha, Kerstin, Staels, Bart, Hofer, Maximilian, Folie, Sabrina, Radlinger, Bernhard, Adolph, Timon E., Rubin, Eduard M., Roden, Michael, Tilg, Herbert, Kaser, Susanne
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apolipoprotein Apolipoprotein A-V - deficiency Apolipoprotein A-V - genetics Biomarkers - blood Blood Glucose - metabolism Diet Dietary Sugars Disease Models, Animal Ectopic fat Fatty Acids - blood Fatty liver Fructose Glucose metabolism Insulin - blood Insulin Resistance Insulin sensitivity Liver - metabolism Mice Mice, Knockout Non-alcoholic Fatty Liver Disease - genetics Non-alcoholic Fatty Liver Disease - metabolism Non-alcoholic Fatty Liver Disease - prevention & control Triglycerides - metabolism
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