Gene Expression-Based Prediction of Neoadjuvant Chemotherapy Response in Early Breast Cancer: Results of the Prospective Multicenter EXPRESSION Trial

Expression-based classifiers to predict pathologic complete response (pCR) after neoadjuvant chemotherapy (NACT) are not routinely used in the clinic. We aimed to build and validate a classifier for pCR after NACT. We performed a prospective multicenter study (EXPRESSION) including 114 patients trea...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical cancer research 2021-04, Vol.27 (8), p.2148-2158
Hauptverfasser:	Edlund, Karolina, Madjar, Katrin, Lebrecht, Antje, Aktas, Bahriye, Pilch, Henryk, Hoffmann, Gerald, Hofmann, Manfred, Kolberg, Hans-Christian, Boehm, Daniel, Battista, Marco, Seehase, Martina, Stewen, Kathrin, Gebhard, Susanne, Cadenas, Cristina, Marchan, Rosemarie, Brenner, Walburgis, Hasenburg, Annette, Koelbl, Heinz, Solbach, Christine, Gehrmann, Mathias, Tanner, Berno, Weber, Karsten E, Loibl, Sibylle, Sachinidis, Agapios, Rahnenführer, Jörg, Schmidt, Marcus, Hengstler, Jan G
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - adverse effects Biomarkers, Tumor - genetics Breast Neoplasms - diagnosis Breast Neoplasms - genetics Breast Neoplasms - therapy Chemotherapy, Adjuvant - methods Clinical Decision-Making - methods Datasets as Topic Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Humans Mastectomy Middle Aged Neoadjuvant Therapy - methods Neoplasm Staging Oligonucleotide Array Sequence Analysis Patient Selection Predictive Value of Tests Prognosis Prospective Studies Treatment Outcome
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!