Cellular prion protein activates Caspase 3 for apoptotic defense mechanism in astrocytes

The cellular prion protein (PrP C ) is anchored in the plasma membrane of cells, and it is highly present in cells of brain tissue, exerting numerous cellular and cognitive functions. The present study proves the importance of PrP C in the cellular defense mechanism and metal homeostasis in astrocyt...

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Veröffentlicht in:	Molecular and cellular biochemistry 2021-05, Vol.476 (5), p.2149-2158
Hauptverfasser:	Marques, Caroline M. S., Pedron, Tatiana, Batista, Bruno L., Cerchiaro, Giselle
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Astrocytes Biochemistry Biomedical and Life Sciences Calcium Calcium (intracellular) Cardiology Caspase-3 Cell cycle Cell death Cell lines Cognitive ability Defense mechanisms Growth rate Homeostasis Inductively coupled plasma mass spectrometry Life Sciences Mass spectrometry Mass spectroscopy Medical Biochemistry Mortality Neurophysiology Oncology p53 Protein Prion protein Prions Proteins Tumor proteins
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