Geranylgeranyl pyrophosphate amplifies Treg differentiation via increased IL‐2 expression to ameliorate DSS‐induced colitis

Blocking the mevalonate pathway for cholesterol reduction by using statin may have adverse effects including statin‐induced colitis. Moreover, one of the predisposing factors for colitis is an imbalanced CD4+ T cell, which can be observed on the complete deletion of HMG‐CoA reductase (HMGCR), a targ...

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