Baseline carotid intima‐media thickness is associated with cardiovascular morbidity and mortality in peritoneal dialysis patients
Carotid intima‐media thickness (CIMT) is an early marker of atherosclerosis and is increased in peritoneal dialysis (PD) patients. Association of CIMT with cardiovascular disease (CVD) or mortality is less clear. Fibroblast growth factor‐23 (FGF‐23) is a hormone associated with vascular calcificatio...
Gespeichert in:
| Veröffentlicht in: | Therapeutic apheresis and dialysis 2021-12, Vol.25 (6), p.962-969 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 969 |
|---|---|
| container_issue | 6 |
| container_start_page | 962 |
| container_title | Therapeutic apheresis and dialysis |
| container_volume | 25 |
| creator | Asicioglu, Ebru Velioglu, Arzu Arikan, Hakki Koc, Mehmet Tuglular, Serhan Ozener, Cetin |
| description | Carotid intima‐media thickness (CIMT) is an early marker of atherosclerosis and is increased in peritoneal dialysis (PD) patients. Association of CIMT with cardiovascular disease (CVD) or mortality is less clear. Fibroblast growth factor‐23 (FGF‐23) is a hormone associated with vascular calcification, atherosclerosis, and mortality in the hemodialysis population. We investigated whether baseline CIMT and FGF‐23 are associated with CVD and mortality in PD patients. Fifty‐five PD patients were included. CVD was defined as ischemic heart disease, stroke, or peripheral artery disease. Intact FGF‐23 was measured in plasma. CIMT was measured by ultrasonography. Twenty‐one patients developed CVD and 12 died over 47.1 ± 33.8 months. Patients with CVD were older (55.9 ± 10.5 vs. 42.5 ± 12.9 years, P |
| doi_str_mv | 10.1111/1744-9987.13629 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2483819473</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2483819473</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3679-a049d09131e1f9a4c8c71c469b6bcae9ae5ab5a9cb61b6501930a46d4adc7c563</originalsourceid><addsrcrecordid>eNqFkLFOHDEQQK0oUSBATRe5THOwPnu965IgIEhIoSC1NWvPiSG-3cPjC7ouUn6Ab8yXZDcH1-LGHuvNK54Qx6o6UeM5VY0xM-fa5kRpO3fvxP7u5_3u3bg98Yn5oarmc6P1R7Gnda1UY9t98ecrMCbqUQbIQ6EoqS-0hL-_n5cYCWS5p_CzR2ZJLIF5CAQFo3yicj_tRBp-AYd1giyXQ-4oUtlI6OM0FUjTRL1cYaYy9AhJjta04dG2gkLYFz4UHxaQGI9e7gPx4_Li7vzb7Ob71fX52c0saNu4GVTGxcoprVAtHJjQhkYFY11nuwDoAGvoanChs6qzdaWcrsDYaCCGJtRWH4gvW-8qD49r5OKXxAFTgh6HNfu5aXWrnGn0iJ5u0ZAH5owLv8pjlbzxqvJTeT-19VNn_7_8uPH5Rb7uxnI7_jX1CNRb4IkSbt7y-buz2634H-b9kno</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2483819473</pqid></control><display><type>article</type><title>Baseline carotid intima‐media thickness is associated with cardiovascular morbidity and mortality in peritoneal dialysis patients</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><creator>Asicioglu, Ebru ; Velioglu, Arzu ; Arikan, Hakki ; Koc, Mehmet ; Tuglular, Serhan ; Ozener, Cetin</creator><creatorcontrib>Asicioglu, Ebru ; Velioglu, Arzu ; Arikan, Hakki ; Koc, Mehmet ; Tuglular, Serhan ; Ozener, Cetin</creatorcontrib><description><![CDATA[Carotid intima‐media thickness (CIMT) is an early marker of atherosclerosis and is increased in peritoneal dialysis (PD) patients. Association of CIMT with cardiovascular disease (CVD) or mortality is less clear. Fibroblast growth factor‐23 (FGF‐23) is a hormone associated with vascular calcification, atherosclerosis, and mortality in the hemodialysis population. We investigated whether baseline CIMT and FGF‐23 are associated with CVD and mortality in PD patients. Fifty‐five PD patients were included. CVD was defined as ischemic heart disease, stroke, or peripheral artery disease. Intact FGF‐23 was measured in plasma. CIMT was measured by ultrasonography. Twenty‐one patients developed CVD and 12 died over 47.1 ± 33.8 months. Patients with CVD were older (55.9 ± 10.5 vs. 42.5 ± 12.9 years, P < .01), had lower albumin (3.8 ± 0.5 vs. 4.2 ± 0.3 g/dL, P < .01) and higher CIMT (0.87 ± 0.22 vs. 0.61 ± 0.11 mm, P < .01). Patients with mortality were also older (53.5 ± 11.5 vs. 45.8 ± 13.8 years, P = .05), had lower albumin (3.7 ± 0.6 vs. 4.1 ± 0.3 g/dL, P < .01), higher CRP (15.0 ± 8.5 vs. 7.6 ± 8.4 mg/L, P < .01) and CIMT (0.9 ± 0.3 vs. 0.6 ± 0.1 mm, P < .01). Albumin and CIMT were associated with CVD and CIMT > 0.75 mm was associated with cardiovascular mortality. FGF‐23 did not show any correlations. CIMT at baseline is associated with CVD and mortality in PD patients.]]></description><identifier>ISSN: 1744-9979</identifier><identifier>EISSN: 1744-9987</identifier><identifier>DOI: 10.1111/1744-9987.13629</identifier><identifier>PMID: 33511768</identifier><language>eng</language><publisher>Kyoto, Japan: John Wiley & Sons Australia, Ltd</publisher><subject>Adult ; Age Factors ; Atherosclerosis - diagnosis ; Atherosclerosis - epidemiology ; cardiovascular disease ; Cardiovascular Diseases - epidemiology ; Cardiovascular Diseases - mortality ; cardiovascular mortality ; Carotid Intima-Media Thickness - statistics & numerical data ; carotid intima‐media thickness ; Comorbidity ; Female ; fibroblast growth factor 23 ; Humans ; Incidence ; Kidney Failure, Chronic - epidemiology ; Kidney Failure, Chronic - therapy ; Male ; Middle Aged ; peritoneal dialysis ; Peritoneal Dialysis - methods ; Turkey - epidemiology</subject><ispartof>Therapeutic apheresis and dialysis, 2021-12, Vol.25 (6), p.962-969</ispartof><rights>2021 International Society for Apheresis, Japanese Society for Apheresis, and Japanese Society for Dialysis Therapy</rights><rights>2021 International Society for Apheresis, Japanese Society for Apheresis, and Japanese Society for Dialysis Therapy.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3679-a049d09131e1f9a4c8c71c469b6bcae9ae5ab5a9cb61b6501930a46d4adc7c563</citedby><cites>FETCH-LOGICAL-c3679-a049d09131e1f9a4c8c71c469b6bcae9ae5ab5a9cb61b6501930a46d4adc7c563</cites><orcidid>0000-0002-5685-115X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2F1744-9987.13629$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2F1744-9987.13629$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33511768$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Asicioglu, Ebru</creatorcontrib><creatorcontrib>Velioglu, Arzu</creatorcontrib><creatorcontrib>Arikan, Hakki</creatorcontrib><creatorcontrib>Koc, Mehmet</creatorcontrib><creatorcontrib>Tuglular, Serhan</creatorcontrib><creatorcontrib>Ozener, Cetin</creatorcontrib><title>Baseline carotid intima‐media thickness is associated with cardiovascular morbidity and mortality in peritoneal dialysis patients</title><title>Therapeutic apheresis and dialysis</title><addtitle>Ther Apher Dial</addtitle><description><![CDATA[Carotid intima‐media thickness (CIMT) is an early marker of atherosclerosis and is increased in peritoneal dialysis (PD) patients. Association of CIMT with cardiovascular disease (CVD) or mortality is less clear. Fibroblast growth factor‐23 (FGF‐23) is a hormone associated with vascular calcification, atherosclerosis, and mortality in the hemodialysis population. We investigated whether baseline CIMT and FGF‐23 are associated with CVD and mortality in PD patients. Fifty‐five PD patients were included. CVD was defined as ischemic heart disease, stroke, or peripheral artery disease. Intact FGF‐23 was measured in plasma. CIMT was measured by ultrasonography. Twenty‐one patients developed CVD and 12 died over 47.1 ± 33.8 months. Patients with CVD were older (55.9 ± 10.5 vs. 42.5 ± 12.9 years, P < .01), had lower albumin (3.8 ± 0.5 vs. 4.2 ± 0.3 g/dL, P < .01) and higher CIMT (0.87 ± 0.22 vs. 0.61 ± 0.11 mm, P < .01). Patients with mortality were also older (53.5 ± 11.5 vs. 45.8 ± 13.8 years, P = .05), had lower albumin (3.7 ± 0.6 vs. 4.1 ± 0.3 g/dL, P < .01), higher CRP (15.0 ± 8.5 vs. 7.6 ± 8.4 mg/L, P < .01) and CIMT (0.9 ± 0.3 vs. 0.6 ± 0.1 mm, P < .01). Albumin and CIMT were associated with CVD and CIMT > 0.75 mm was associated with cardiovascular mortality. FGF‐23 did not show any correlations. CIMT at baseline is associated with CVD and mortality in PD patients.]]></description><subject>Adult</subject><subject>Age Factors</subject><subject>Atherosclerosis - diagnosis</subject><subject>Atherosclerosis - epidemiology</subject><subject>cardiovascular disease</subject><subject>Cardiovascular Diseases - epidemiology</subject><subject>Cardiovascular Diseases - mortality</subject><subject>cardiovascular mortality</subject><subject>Carotid Intima-Media Thickness - statistics & numerical data</subject><subject>carotid intima‐media thickness</subject><subject>Comorbidity</subject><subject>Female</subject><subject>fibroblast growth factor 23</subject><subject>Humans</subject><subject>Incidence</subject><subject>Kidney Failure, Chronic - epidemiology</subject><subject>Kidney Failure, Chronic - therapy</subject><subject>Male</subject><subject>Middle Aged</subject><subject>peritoneal dialysis</subject><subject>Peritoneal Dialysis - methods</subject><subject>Turkey - epidemiology</subject><issn>1744-9979</issn><issn>1744-9987</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkLFOHDEQQK0oUSBATRe5THOwPnu965IgIEhIoSC1NWvPiSG-3cPjC7ouUn6Ab8yXZDcH1-LGHuvNK54Qx6o6UeM5VY0xM-fa5kRpO3fvxP7u5_3u3bg98Yn5oarmc6P1R7Gnda1UY9t98ecrMCbqUQbIQ6EoqS-0hL-_n5cYCWS5p_CzR2ZJLIF5CAQFo3yicj_tRBp-AYd1giyXQ-4oUtlI6OM0FUjTRL1cYaYy9AhJjta04dG2gkLYFz4UHxaQGI9e7gPx4_Li7vzb7Ob71fX52c0saNu4GVTGxcoprVAtHJjQhkYFY11nuwDoAGvoanChs6qzdaWcrsDYaCCGJtRWH4gvW-8qD49r5OKXxAFTgh6HNfu5aXWrnGn0iJ5u0ZAH5owLv8pjlbzxqvJTeT-19VNn_7_8uPH5Rb7uxnI7_jX1CNRb4IkSbt7y-buz2634H-b9kno</recordid><startdate>202112</startdate><enddate>202112</enddate><creator>Asicioglu, Ebru</creator><creator>Velioglu, Arzu</creator><creator>Arikan, Hakki</creator><creator>Koc, Mehmet</creator><creator>Tuglular, Serhan</creator><creator>Ozener, Cetin</creator><general>John Wiley & Sons Australia, Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-5685-115X</orcidid></search><sort><creationdate>202112</creationdate><title>Baseline carotid intima‐media thickness is associated with cardiovascular morbidity and mortality in peritoneal dialysis patients</title><author>Asicioglu, Ebru ; Velioglu, Arzu ; Arikan, Hakki ; Koc, Mehmet ; Tuglular, Serhan ; Ozener, Cetin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3679-a049d09131e1f9a4c8c71c469b6bcae9ae5ab5a9cb61b6501930a46d4adc7c563</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Atherosclerosis - diagnosis</topic><topic>Atherosclerosis - epidemiology</topic><topic>cardiovascular disease</topic><topic>Cardiovascular Diseases - epidemiology</topic><topic>Cardiovascular Diseases - mortality</topic><topic>cardiovascular mortality</topic><topic>Carotid Intima-Media Thickness - statistics & numerical data</topic><topic>carotid intima‐media thickness</topic><topic>Comorbidity</topic><topic>Female</topic><topic>fibroblast growth factor 23</topic><topic>Humans</topic><topic>Incidence</topic><topic>Kidney Failure, Chronic - epidemiology</topic><topic>Kidney Failure, Chronic - therapy</topic><topic>Male</topic><topic>Middle Aged</topic><topic>peritoneal dialysis</topic><topic>Peritoneal Dialysis - methods</topic><topic>Turkey - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Asicioglu, Ebru</creatorcontrib><creatorcontrib>Velioglu, Arzu</creatorcontrib><creatorcontrib>Arikan, Hakki</creatorcontrib><creatorcontrib>Koc, Mehmet</creatorcontrib><creatorcontrib>Tuglular, Serhan</creatorcontrib><creatorcontrib>Ozener, Cetin</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Therapeutic apheresis and dialysis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Asicioglu, Ebru</au><au>Velioglu, Arzu</au><au>Arikan, Hakki</au><au>Koc, Mehmet</au><au>Tuglular, Serhan</au><au>Ozener, Cetin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Baseline carotid intima‐media thickness is associated with cardiovascular morbidity and mortality in peritoneal dialysis patients</atitle><jtitle>Therapeutic apheresis and dialysis</jtitle><addtitle>Ther Apher Dial</addtitle><date>2021-12</date><risdate>2021</risdate><volume>25</volume><issue>6</issue><spage>962</spage><epage>969</epage><pages>962-969</pages><issn>1744-9979</issn><eissn>1744-9987</eissn><abstract><![CDATA[Carotid intima‐media thickness (CIMT) is an early marker of atherosclerosis and is increased in peritoneal dialysis (PD) patients. Association of CIMT with cardiovascular disease (CVD) or mortality is less clear. Fibroblast growth factor‐23 (FGF‐23) is a hormone associated with vascular calcification, atherosclerosis, and mortality in the hemodialysis population. We investigated whether baseline CIMT and FGF‐23 are associated with CVD and mortality in PD patients. Fifty‐five PD patients were included. CVD was defined as ischemic heart disease, stroke, or peripheral artery disease. Intact FGF‐23 was measured in plasma. CIMT was measured by ultrasonography. Twenty‐one patients developed CVD and 12 died over 47.1 ± 33.8 months. Patients with CVD were older (55.9 ± 10.5 vs. 42.5 ± 12.9 years, P < .01), had lower albumin (3.8 ± 0.5 vs. 4.2 ± 0.3 g/dL, P < .01) and higher CIMT (0.87 ± 0.22 vs. 0.61 ± 0.11 mm, P < .01). Patients with mortality were also older (53.5 ± 11.5 vs. 45.8 ± 13.8 years, P = .05), had lower albumin (3.7 ± 0.6 vs. 4.1 ± 0.3 g/dL, P < .01), higher CRP (15.0 ± 8.5 vs. 7.6 ± 8.4 mg/L, P < .01) and CIMT (0.9 ± 0.3 vs. 0.6 ± 0.1 mm, P < .01). Albumin and CIMT were associated with CVD and CIMT > 0.75 mm was associated with cardiovascular mortality. FGF‐23 did not show any correlations. CIMT at baseline is associated with CVD and mortality in PD patients.]]></abstract><cop>Kyoto, Japan</cop><pub>John Wiley & Sons Australia, Ltd</pub><pmid>33511768</pmid><doi>10.1111/1744-9987.13629</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-5685-115X</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1744-9979 |
| ispartof | Therapeutic apheresis and dialysis, 2021-12, Vol.25 (6), p.962-969 |
| issn | 1744-9979 1744-9987 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2483819473 |
| source | MEDLINE; Access via Wiley Online Library |
| subjects | Adult Age Factors Atherosclerosis - diagnosis Atherosclerosis - epidemiology cardiovascular disease Cardiovascular Diseases - epidemiology Cardiovascular Diseases - mortality cardiovascular mortality Carotid Intima-Media Thickness - statistics & numerical data carotid intima‐media thickness Comorbidity Female fibroblast growth factor 23 Humans Incidence Kidney Failure, Chronic - epidemiology Kidney Failure, Chronic - therapy Male Middle Aged peritoneal dialysis Peritoneal Dialysis - methods Turkey - epidemiology |
| title | Baseline carotid intima‐media thickness is associated with cardiovascular morbidity and mortality in peritoneal dialysis patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T20%3A32%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Baseline%20carotid%20intima%E2%80%90media%20thickness%20is%20associated%20with%20cardiovascular%20morbidity%20and%20mortality%20in%20peritoneal%20dialysis%20patients&rft.jtitle=Therapeutic%20apheresis%20and%20dialysis&rft.au=Asicioglu,%20Ebru&rft.date=2021-12&rft.volume=25&rft.issue=6&rft.spage=962&rft.epage=969&rft.pages=962-969&rft.issn=1744-9979&rft.eissn=1744-9987&rft_id=info:doi/10.1111/1744-9987.13629&rft_dat=%3Cproquest_cross%3E2483819473%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2483819473&rft_id=info:pmid/33511768&rfr_iscdi=true |