Psychological profile and unexpected pain in oral lichen planus: A case–control multicenter SIPMO studya
Objectives To analyze psychological profiles, pain, and oral symptoms in patients with oral lichen planus (OLP). Materials and methods 300 patients with keratotic OLP (K‐OLP; reticular, papular, plaque‐like subtypes), 300 patients with predominant non‐keratotic OLP (nK‐OLP; erythematosus atrophic, e...
Gespeichert in:
| Veröffentlicht in: | Oral diseases 2022-03, Vol.28 (2), p.398-414 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 414 |
|---|---|
| container_issue | 2 |
| container_start_page | 398 |
| container_title | Oral diseases |
| container_volume | 28 |
| creator | Adamo, Daniela Calabria, Elena Coppola, Noemi Lo Muzio, Lorenzo Giuliani, Michele Bizzoca, Maria Eleonora Azzi, Lorenzo Croveri, Fabio Colella, Giuseppe Boschetti, Ciro Emiliano Montebugnoli, Lucio Gissi, Davide Gabriele, Mario Nisi, Marco Sardella, Andrea Lodi, Giovanni Varoni, Elena M. Giudice, Amerigo Antonelli, Alessandro Cabras, Marco Gambino, Alessio Vescovi, Paolo Majorana, Alessandra Bardellini, Elena Campisi, Giuseppina Panzarella, Vera Francesco, Spadari Marino, Sonia Pentenero, Monica Ardore, Marco Biasotto, Matteo Gobbo, Margherita Guarda Nardini, Luca Romeo, Umberto Tenore, Gianluca Serpico, Rosario Lajolo, Carlo Gioco, Gioele Aria, Massimo Mignogna, Michele Davide |
| description | Objectives
To analyze psychological profiles, pain, and oral symptoms in patients with oral lichen planus (OLP).
Materials and methods
300 patients with keratotic OLP (K‐OLP; reticular, papular, plaque‐like subtypes), 300 patients with predominant non‐keratotic OLP (nK‐OLP; erythematosus atrophic, erosive, ulcerative, bullous subtypes), and 300 controls were recruited in 15 universities. The number of oral sites involved and oral symptoms were recorded. The Numeric Rating Scale (NRS), Total Pain Rating Index (T‐PRI), Hamilton Rating Scales for Depression and for Anxiety (HAM‐D and HAM‐A), Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleepiness Scale (ESS) were administered.
Results
The OLP patients, especially the nK‐OLP, showed higher scores in the NRS, T‐PRI, HAM‐D, HAM‐A and PSQI compared with the controls (p‐value |
| doi_str_mv | 10.1111/odi.13787 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_wiley</sourceid><recordid>TN_cdi_proquest_miscellaneous_2483818880</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2629285153</sourcerecordid><originalsourceid>FETCH-LOGICAL-p1367-28de1b48978de57b6f132abaa1e0289ede8ce1c7cd91c0637686c57c83d4a0393</originalsourceid><addsrcrecordid>eNpdkM1KAzEQx4MoWKsH3yDgxcu2-ehust5K_SpUWlDBW0iTqd2SbtbNLro338E39EmMrSeHgfkffgwzP4TOKRnQWENviwHlQooD1KMZoQmRLD2MmaejJGX85RidhLAhhIqcsx7aLEJn1t7518Joh6varwoHWJcWtyV8VGAasLjSRYlj-zoyrjBrKHHldNmGKzzGRgf4_vwyvmxq7_C2dU1hoGygxo_TxcMch6a1nT5FRyvtApz9zT56vr15mtwns_nddDKeJRXlmUiYtECXI5mLGFKxzFaUM73UmgJhMgcL0gA1wticGpJxkcnMpMJIbkea8Jz30eV-b3zmrYXQqG0RDLh4L_g2KDaSXFIpJYnoxT9049u6jNcplrGcyZSmPFLDPfUe1XSqqoutrjtFifpVrqJytVOu5tfTXeA_43l3Uw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2629285153</pqid></control><display><type>article</type><title>Psychological profile and unexpected pain in oral lichen planus: A case–control multicenter SIPMO studya</title><source>Wiley Online Library - AutoHoldings Journals</source><creator>Adamo, Daniela ; Calabria, Elena ; Coppola, Noemi ; Lo Muzio, Lorenzo ; Giuliani, Michele ; Bizzoca, Maria Eleonora ; Azzi, Lorenzo ; Croveri, Fabio ; Colella, Giuseppe ; Boschetti, Ciro Emiliano ; Montebugnoli, Lucio ; Gissi, Davide ; Gabriele, Mario ; Nisi, Marco ; Sardella, Andrea ; Lodi, Giovanni ; Varoni, Elena M. ; Giudice, Amerigo ; Antonelli, Alessandro ; Cabras, Marco ; Gambino, Alessio ; Vescovi, Paolo ; Majorana, Alessandra ; Bardellini, Elena ; Campisi, Giuseppina ; Panzarella, Vera ; Francesco, Spadari ; Marino, Sonia ; Pentenero, Monica ; Ardore, Marco ; Biasotto, Matteo ; Gobbo, Margherita ; Guarda Nardini, Luca ; Romeo, Umberto ; Tenore, Gianluca ; Serpico, Rosario ; Lajolo, Carlo ; Gioco, Gioele ; Aria, Massimo ; Mignogna, Michele Davide</creator><creatorcontrib>Adamo, Daniela ; Calabria, Elena ; Coppola, Noemi ; Lo Muzio, Lorenzo ; Giuliani, Michele ; Bizzoca, Maria Eleonora ; Azzi, Lorenzo ; Croveri, Fabio ; Colella, Giuseppe ; Boschetti, Ciro Emiliano ; Montebugnoli, Lucio ; Gissi, Davide ; Gabriele, Mario ; Nisi, Marco ; Sardella, Andrea ; Lodi, Giovanni ; Varoni, Elena M. ; Giudice, Amerigo ; Antonelli, Alessandro ; Cabras, Marco ; Gambino, Alessio ; Vescovi, Paolo ; Majorana, Alessandra ; Bardellini, Elena ; Campisi, Giuseppina ; Panzarella, Vera ; Francesco, Spadari ; Marino, Sonia ; Pentenero, Monica ; Ardore, Marco ; Biasotto, Matteo ; Gobbo, Margherita ; Guarda Nardini, Luca ; Romeo, Umberto ; Tenore, Gianluca ; Serpico, Rosario ; Lajolo, Carlo ; Gioco, Gioele ; Aria, Massimo ; Mignogna, Michele Davide</creatorcontrib><description>Objectives
To analyze psychological profiles, pain, and oral symptoms in patients with oral lichen planus (OLP).
Materials and methods
300 patients with keratotic OLP (K‐OLP; reticular, papular, plaque‐like subtypes), 300 patients with predominant non‐keratotic OLP (nK‐OLP; erythematosus atrophic, erosive, ulcerative, bullous subtypes), and 300 controls were recruited in 15 universities. The number of oral sites involved and oral symptoms were recorded. The Numeric Rating Scale (NRS), Total Pain Rating Index (T‐PRI), Hamilton Rating Scales for Depression and for Anxiety (HAM‐D and HAM‐A), Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleepiness Scale (ESS) were administered.
Results
The OLP patients, especially the nK‐OLP, showed higher scores in the NRS, T‐PRI, HAM‐D, HAM‐A and PSQI compared with the controls (p‐value < .001**). A positive correlation between the NRS, T‐PRI, HAM‐A, HAM‐D, and PSQI was found with the number of oral symptoms and number of oral sites involved. Pain was reported in 67.3% of nK‐OLP and 49.7% of K‐OLP cases with poor correspondence between the site of lesions and the site of the symptoms.
Conclusions
Mood disorders are frequently associated with OLP with an unexpected symptomatology correlated with the number of oral symptoms and with the extension of disease suggesting a peripheral neuropathy.</description><identifier>ISSN: 1354-523X</identifier><identifier>EISSN: 1601-0825</identifier><identifier>DOI: 10.1111/odi.13787</identifier><language>eng</language><publisher>Malden: Wiley Subscription Services, Inc</publisher><subject>anxiety ; Dentistry ; depression ; Lichen planus ; oral lichen planus ; Pain ; Peripheral neuropathy ; Sleep and wakefulness ; sleep disturbance</subject><ispartof>Oral diseases, 2022-03, Vol.28 (2), p.398-414</ispartof><rights>2021 Wiley Periodicals LLC</rights><rights>2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><orcidid>0000-0003-2532-7651 ; 0000-0003-3972-1203 ; 0000-0002-0218-8292 ; 0000-0002-8637-2029 ; 0000-0003-0739-5650 ; 0000-0003-4491-4640 ; 0000-0002-5091-6979 ; 0000-0002-8240-5874 ; 0000-0002-3784-4229 ; 0000-0002-3955-4794</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fodi.13787$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fodi.13787$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,781,785,1418,27929,27930,45579,45580</link.rule.ids></links><search><creatorcontrib>Adamo, Daniela</creatorcontrib><creatorcontrib>Calabria, Elena</creatorcontrib><creatorcontrib>Coppola, Noemi</creatorcontrib><creatorcontrib>Lo Muzio, Lorenzo</creatorcontrib><creatorcontrib>Giuliani, Michele</creatorcontrib><creatorcontrib>Bizzoca, Maria Eleonora</creatorcontrib><creatorcontrib>Azzi, Lorenzo</creatorcontrib><creatorcontrib>Croveri, Fabio</creatorcontrib><creatorcontrib>Colella, Giuseppe</creatorcontrib><creatorcontrib>Boschetti, Ciro Emiliano</creatorcontrib><creatorcontrib>Montebugnoli, Lucio</creatorcontrib><creatorcontrib>Gissi, Davide</creatorcontrib><creatorcontrib>Gabriele, Mario</creatorcontrib><creatorcontrib>Nisi, Marco</creatorcontrib><creatorcontrib>Sardella, Andrea</creatorcontrib><creatorcontrib>Lodi, Giovanni</creatorcontrib><creatorcontrib>Varoni, Elena M.</creatorcontrib><creatorcontrib>Giudice, Amerigo</creatorcontrib><creatorcontrib>Antonelli, Alessandro</creatorcontrib><creatorcontrib>Cabras, Marco</creatorcontrib><creatorcontrib>Gambino, Alessio</creatorcontrib><creatorcontrib>Vescovi, Paolo</creatorcontrib><creatorcontrib>Majorana, Alessandra</creatorcontrib><creatorcontrib>Bardellini, Elena</creatorcontrib><creatorcontrib>Campisi, Giuseppina</creatorcontrib><creatorcontrib>Panzarella, Vera</creatorcontrib><creatorcontrib>Francesco, Spadari</creatorcontrib><creatorcontrib>Marino, Sonia</creatorcontrib><creatorcontrib>Pentenero, Monica</creatorcontrib><creatorcontrib>Ardore, Marco</creatorcontrib><creatorcontrib>Biasotto, Matteo</creatorcontrib><creatorcontrib>Gobbo, Margherita</creatorcontrib><creatorcontrib>Guarda Nardini, Luca</creatorcontrib><creatorcontrib>Romeo, Umberto</creatorcontrib><creatorcontrib>Tenore, Gianluca</creatorcontrib><creatorcontrib>Serpico, Rosario</creatorcontrib><creatorcontrib>Lajolo, Carlo</creatorcontrib><creatorcontrib>Gioco, Gioele</creatorcontrib><creatorcontrib>Aria, Massimo</creatorcontrib><creatorcontrib>Mignogna, Michele Davide</creatorcontrib><title>Psychological profile and unexpected pain in oral lichen planus: A case–control multicenter SIPMO studya</title><title>Oral diseases</title><description>Objectives
To analyze psychological profiles, pain, and oral symptoms in patients with oral lichen planus (OLP).
Materials and methods
300 patients with keratotic OLP (K‐OLP; reticular, papular, plaque‐like subtypes), 300 patients with predominant non‐keratotic OLP (nK‐OLP; erythematosus atrophic, erosive, ulcerative, bullous subtypes), and 300 controls were recruited in 15 universities. The number of oral sites involved and oral symptoms were recorded. The Numeric Rating Scale (NRS), Total Pain Rating Index (T‐PRI), Hamilton Rating Scales for Depression and for Anxiety (HAM‐D and HAM‐A), Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleepiness Scale (ESS) were administered.
Results
The OLP patients, especially the nK‐OLP, showed higher scores in the NRS, T‐PRI, HAM‐D, HAM‐A and PSQI compared with the controls (p‐value < .001**). A positive correlation between the NRS, T‐PRI, HAM‐A, HAM‐D, and PSQI was found with the number of oral symptoms and number of oral sites involved. Pain was reported in 67.3% of nK‐OLP and 49.7% of K‐OLP cases with poor correspondence between the site of lesions and the site of the symptoms.
Conclusions
Mood disorders are frequently associated with OLP with an unexpected symptomatology correlated with the number of oral symptoms and with the extension of disease suggesting a peripheral neuropathy.</description><subject>anxiety</subject><subject>Dentistry</subject><subject>depression</subject><subject>Lichen planus</subject><subject>oral lichen planus</subject><subject>Pain</subject><subject>Peripheral neuropathy</subject><subject>Sleep and wakefulness</subject><subject>sleep disturbance</subject><issn>1354-523X</issn><issn>1601-0825</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNpdkM1KAzEQx4MoWKsH3yDgxcu2-ehust5K_SpUWlDBW0iTqd2SbtbNLro338E39EmMrSeHgfkffgwzP4TOKRnQWENviwHlQooD1KMZoQmRLD2MmaejJGX85RidhLAhhIqcsx7aLEJn1t7518Joh6varwoHWJcWtyV8VGAasLjSRYlj-zoyrjBrKHHldNmGKzzGRgf4_vwyvmxq7_C2dU1hoGygxo_TxcMch6a1nT5FRyvtApz9zT56vr15mtwns_nddDKeJRXlmUiYtECXI5mLGFKxzFaUM73UmgJhMgcL0gA1wticGpJxkcnMpMJIbkea8Jz30eV-b3zmrYXQqG0RDLh4L_g2KDaSXFIpJYnoxT9049u6jNcplrGcyZSmPFLDPfUe1XSqqoutrjtFifpVrqJytVOu5tfTXeA_43l3Uw</recordid><startdate>202203</startdate><enddate>202203</enddate><creator>Adamo, Daniela</creator><creator>Calabria, Elena</creator><creator>Coppola, Noemi</creator><creator>Lo Muzio, Lorenzo</creator><creator>Giuliani, Michele</creator><creator>Bizzoca, Maria Eleonora</creator><creator>Azzi, Lorenzo</creator><creator>Croveri, Fabio</creator><creator>Colella, Giuseppe</creator><creator>Boschetti, Ciro Emiliano</creator><creator>Montebugnoli, Lucio</creator><creator>Gissi, Davide</creator><creator>Gabriele, Mario</creator><creator>Nisi, Marco</creator><creator>Sardella, Andrea</creator><creator>Lodi, Giovanni</creator><creator>Varoni, Elena M.</creator><creator>Giudice, Amerigo</creator><creator>Antonelli, Alessandro</creator><creator>Cabras, Marco</creator><creator>Gambino, Alessio</creator><creator>Vescovi, Paolo</creator><creator>Majorana, Alessandra</creator><creator>Bardellini, Elena</creator><creator>Campisi, Giuseppina</creator><creator>Panzarella, Vera</creator><creator>Francesco, Spadari</creator><creator>Marino, Sonia</creator><creator>Pentenero, Monica</creator><creator>Ardore, Marco</creator><creator>Biasotto, Matteo</creator><creator>Gobbo, Margherita</creator><creator>Guarda Nardini, Luca</creator><creator>Romeo, Umberto</creator><creator>Tenore, Gianluca</creator><creator>Serpico, Rosario</creator><creator>Lajolo, Carlo</creator><creator>Gioco, Gioele</creator><creator>Aria, Massimo</creator><creator>Mignogna, Michele Davide</creator><general>Wiley Subscription Services, Inc</general><scope>7QP</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-2532-7651</orcidid><orcidid>https://orcid.org/0000-0003-3972-1203</orcidid><orcidid>https://orcid.org/0000-0002-0218-8292</orcidid><orcidid>https://orcid.org/0000-0002-8637-2029</orcidid><orcidid>https://orcid.org/0000-0003-0739-5650</orcidid><orcidid>https://orcid.org/0000-0003-4491-4640</orcidid><orcidid>https://orcid.org/0000-0002-5091-6979</orcidid><orcidid>https://orcid.org/0000-0002-8240-5874</orcidid><orcidid>https://orcid.org/0000-0002-3784-4229</orcidid><orcidid>https://orcid.org/0000-0002-3955-4794</orcidid></search><sort><creationdate>202203</creationdate><title>Psychological profile and unexpected pain in oral lichen planus: A case–control multicenter SIPMO studya</title><author>Adamo, Daniela ; Calabria, Elena ; Coppola, Noemi ; Lo Muzio, Lorenzo ; Giuliani, Michele ; Bizzoca, Maria Eleonora ; Azzi, Lorenzo ; Croveri, Fabio ; Colella, Giuseppe ; Boschetti, Ciro Emiliano ; Montebugnoli, Lucio ; Gissi, Davide ; Gabriele, Mario ; Nisi, Marco ; Sardella, Andrea ; Lodi, Giovanni ; Varoni, Elena M. ; Giudice, Amerigo ; Antonelli, Alessandro ; Cabras, Marco ; Gambino, Alessio ; Vescovi, Paolo ; Majorana, Alessandra ; Bardellini, Elena ; Campisi, Giuseppina ; Panzarella, Vera ; Francesco, Spadari ; Marino, Sonia ; Pentenero, Monica ; Ardore, Marco ; Biasotto, Matteo ; Gobbo, Margherita ; Guarda Nardini, Luca ; Romeo, Umberto ; Tenore, Gianluca ; Serpico, Rosario ; Lajolo, Carlo ; Gioco, Gioele ; Aria, Massimo ; Mignogna, Michele Davide</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p1367-28de1b48978de57b6f132abaa1e0289ede8ce1c7cd91c0637686c57c83d4a0393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>anxiety</topic><topic>Dentistry</topic><topic>depression</topic><topic>Lichen planus</topic><topic>oral lichen planus</topic><topic>Pain</topic><topic>Peripheral neuropathy</topic><topic>Sleep and wakefulness</topic><topic>sleep disturbance</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Adamo, Daniela</creatorcontrib><creatorcontrib>Calabria, Elena</creatorcontrib><creatorcontrib>Coppola, Noemi</creatorcontrib><creatorcontrib>Lo Muzio, Lorenzo</creatorcontrib><creatorcontrib>Giuliani, Michele</creatorcontrib><creatorcontrib>Bizzoca, Maria Eleonora</creatorcontrib><creatorcontrib>Azzi, Lorenzo</creatorcontrib><creatorcontrib>Croveri, Fabio</creatorcontrib><creatorcontrib>Colella, Giuseppe</creatorcontrib><creatorcontrib>Boschetti, Ciro Emiliano</creatorcontrib><creatorcontrib>Montebugnoli, Lucio</creatorcontrib><creatorcontrib>Gissi, Davide</creatorcontrib><creatorcontrib>Gabriele, Mario</creatorcontrib><creatorcontrib>Nisi, Marco</creatorcontrib><creatorcontrib>Sardella, Andrea</creatorcontrib><creatorcontrib>Lodi, Giovanni</creatorcontrib><creatorcontrib>Varoni, Elena M.</creatorcontrib><creatorcontrib>Giudice, Amerigo</creatorcontrib><creatorcontrib>Antonelli, Alessandro</creatorcontrib><creatorcontrib>Cabras, Marco</creatorcontrib><creatorcontrib>Gambino, Alessio</creatorcontrib><creatorcontrib>Vescovi, Paolo</creatorcontrib><creatorcontrib>Majorana, Alessandra</creatorcontrib><creatorcontrib>Bardellini, Elena</creatorcontrib><creatorcontrib>Campisi, Giuseppina</creatorcontrib><creatorcontrib>Panzarella, Vera</creatorcontrib><creatorcontrib>Francesco, Spadari</creatorcontrib><creatorcontrib>Marino, Sonia</creatorcontrib><creatorcontrib>Pentenero, Monica</creatorcontrib><creatorcontrib>Ardore, Marco</creatorcontrib><creatorcontrib>Biasotto, Matteo</creatorcontrib><creatorcontrib>Gobbo, Margherita</creatorcontrib><creatorcontrib>Guarda Nardini, Luca</creatorcontrib><creatorcontrib>Romeo, Umberto</creatorcontrib><creatorcontrib>Tenore, Gianluca</creatorcontrib><creatorcontrib>Serpico, Rosario</creatorcontrib><creatorcontrib>Lajolo, Carlo</creatorcontrib><creatorcontrib>Gioco, Gioele</creatorcontrib><creatorcontrib>Aria, Massimo</creatorcontrib><creatorcontrib>Mignogna, Michele Davide</creatorcontrib><collection>Calcium & Calcified Tissue Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Oral diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Adamo, Daniela</au><au>Calabria, Elena</au><au>Coppola, Noemi</au><au>Lo Muzio, Lorenzo</au><au>Giuliani, Michele</au><au>Bizzoca, Maria Eleonora</au><au>Azzi, Lorenzo</au><au>Croveri, Fabio</au><au>Colella, Giuseppe</au><au>Boschetti, Ciro Emiliano</au><au>Montebugnoli, Lucio</au><au>Gissi, Davide</au><au>Gabriele, Mario</au><au>Nisi, Marco</au><au>Sardella, Andrea</au><au>Lodi, Giovanni</au><au>Varoni, Elena M.</au><au>Giudice, Amerigo</au><au>Antonelli, Alessandro</au><au>Cabras, Marco</au><au>Gambino, Alessio</au><au>Vescovi, Paolo</au><au>Majorana, Alessandra</au><au>Bardellini, Elena</au><au>Campisi, Giuseppina</au><au>Panzarella, Vera</au><au>Francesco, Spadari</au><au>Marino, Sonia</au><au>Pentenero, Monica</au><au>Ardore, Marco</au><au>Biasotto, Matteo</au><au>Gobbo, Margherita</au><au>Guarda Nardini, Luca</au><au>Romeo, Umberto</au><au>Tenore, Gianluca</au><au>Serpico, Rosario</au><au>Lajolo, Carlo</au><au>Gioco, Gioele</au><au>Aria, Massimo</au><au>Mignogna, Michele Davide</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Psychological profile and unexpected pain in oral lichen planus: A case–control multicenter SIPMO studya</atitle><jtitle>Oral diseases</jtitle><date>2022-03</date><risdate>2022</risdate><volume>28</volume><issue>2</issue><spage>398</spage><epage>414</epage><pages>398-414</pages><issn>1354-523X</issn><eissn>1601-0825</eissn><abstract>Objectives
To analyze psychological profiles, pain, and oral symptoms in patients with oral lichen planus (OLP).
Materials and methods
300 patients with keratotic OLP (K‐OLP; reticular, papular, plaque‐like subtypes), 300 patients with predominant non‐keratotic OLP (nK‐OLP; erythematosus atrophic, erosive, ulcerative, bullous subtypes), and 300 controls were recruited in 15 universities. The number of oral sites involved and oral symptoms were recorded. The Numeric Rating Scale (NRS), Total Pain Rating Index (T‐PRI), Hamilton Rating Scales for Depression and for Anxiety (HAM‐D and HAM‐A), Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleepiness Scale (ESS) were administered.
Results
The OLP patients, especially the nK‐OLP, showed higher scores in the NRS, T‐PRI, HAM‐D, HAM‐A and PSQI compared with the controls (p‐value < .001**). A positive correlation between the NRS, T‐PRI, HAM‐A, HAM‐D, and PSQI was found with the number of oral symptoms and number of oral sites involved. Pain was reported in 67.3% of nK‐OLP and 49.7% of K‐OLP cases with poor correspondence between the site of lesions and the site of the symptoms.
Conclusions
Mood disorders are frequently associated with OLP with an unexpected symptomatology correlated with the number of oral symptoms and with the extension of disease suggesting a peripheral neuropathy.</abstract><cop>Malden</cop><pub>Wiley Subscription Services, Inc</pub><doi>10.1111/odi.13787</doi><tpages>0</tpages><orcidid>https://orcid.org/0000-0003-2532-7651</orcidid><orcidid>https://orcid.org/0000-0003-3972-1203</orcidid><orcidid>https://orcid.org/0000-0002-0218-8292</orcidid><orcidid>https://orcid.org/0000-0002-8637-2029</orcidid><orcidid>https://orcid.org/0000-0003-0739-5650</orcidid><orcidid>https://orcid.org/0000-0003-4491-4640</orcidid><orcidid>https://orcid.org/0000-0002-5091-6979</orcidid><orcidid>https://orcid.org/0000-0002-8240-5874</orcidid><orcidid>https://orcid.org/0000-0002-3784-4229</orcidid><orcidid>https://orcid.org/0000-0002-3955-4794</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1354-523X |
| ispartof | Oral diseases, 2022-03, Vol.28 (2), p.398-414 |
| issn | 1354-523X 1601-0825 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2483818880 |
| source | Wiley Online Library - AutoHoldings Journals |
| subjects | anxiety Dentistry depression Lichen planus oral lichen planus Pain Peripheral neuropathy Sleep and wakefulness sleep disturbance |
| title | Psychological profile and unexpected pain in oral lichen planus: A case–control multicenter SIPMO studya |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-12T07%3A11%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_wiley&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Psychological%20profile%20and%20unexpected%20pain%20in%20oral%20lichen%20planus:%20A%20case%E2%80%93control%20multicenter%20SIPMO%20studya&rft.jtitle=Oral%20diseases&rft.au=Adamo,%20Daniela&rft.date=2022-03&rft.volume=28&rft.issue=2&rft.spage=398&rft.epage=414&rft.pages=398-414&rft.issn=1354-523X&rft.eissn=1601-0825&rft_id=info:doi/10.1111/odi.13787&rft_dat=%3Cproquest_wiley%3E2629285153%3C/proquest_wiley%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2629285153&rft_id=info:pmid/&rfr_iscdi=true |