Synergistic interaction between B vitamins and statins to counter nociception in rats

Evidence suggests that the antinociceptive activity of various drugs can be increased when administered in combination with B vitamins (BVs). The aim of this study was to examine the potential interaction between statins and BVs to counter nociception, the latter measured by the formalin test. Rats...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Drug development research 2021-05, Vol.82 (3), p.440-447
Hauptverfasser:	Skiold, López‐Canales Jorge, Estefania, Ruiz‐Pedraza Paola, Carolina, García‐Paz María Paola, Mery, López‐Mayorga Ruth, Fernando, Castillo‐Henkel Enrique, Jair, Lozano‐Cuenca
Format:	Artikel
Sprache:	eng
Schlagworte:	analgesia Animals Atorvastatin B vitamins Drug Synergism formalin test Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology isobolographic analysis Male Mathematical analysis Nociception - drug effects Oral administration Pain Pain Measurement Pain perception pharmacology Pravastatin Rats Rats, Wistar Statins Vitamin B Complex - pharmacology Vitamins
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!