The Novel Membrane-Associated Auxiliary Factors AuxA and AuxB Modulate β-lactam Resistance in MRSA by stabilizing Lipoteichoic Acids

•AuxA and AuxB are two novel auxiliary factors of β-lactam resistance in methicillin-resistant Staphylococcus aureus (MRSA)•aux mutants share phenotypes with mutants defective in lipoteichoic acid (LTA) synthesis•LTAs are released into the growth media by auxA and auxB mutants•LTA stability is impor...

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Veröffentlicht in:	International journal of antimicrobial agents 2021-03, Vol.57 (3), p.106283-106283, Article 106283
Hauptverfasser:	Mikkelsen, Kasper, Sirisarn, Wanchat, Alharbi, Ohood, Alharbi, Mohanned, Liu, Huayong, Nøhr-Meldgaard, Katrine, Mayer, Katharina, Vestergaard, Martin, Gallagher, Laura A., Derrick, Jeremy P., McBain, Andrew J, Biboy, Jacob, Vollmer, Waldemar, O'Gara, James P., Grunert, Tom, Ingmer, Hanne, Xia, Guoqing
Format:	Artikel
Sprache:	eng
Schlagworte:	antibiotic resistance auxA auxB auxiliary factor lipoteichoic acid methicillin-resistant Staphylococcus aureus β-lactam resistance
Online-Zugang:	Volltext
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