Real-Time Visualization and Quantification of Oncolytic M1 Virus In Vitro and In Vivo

Alphavirus M1 is a promising oncolytic virus for cancer therapy. Here, we constructed a fluorescent reporter virus for real-time visualization and quantification of M1 virus both and . The reporter-encoding M1 virus maintained the characteristics of parental virus in the aspects of structure, replic...

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Veröffentlicht in:	Human gene therapy 2021-02, Vol.32 (3-4), p.158-165
Hauptverfasser:	Zhu, Wenbo, Liang, Jiankai, Tan, Jingyi, Guo, Li, Cai, Jing, Hu, Jun, Yan, Guangmei, Liu, Yang, Zhang, Jiayu, Song, Deli, Dan, Jia, Wong, Chun-Wa, Su, Xingwen, Qiu, Pengxin, Lin, Yuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Alphavirus - genetics Cell death Cell Line, Tumor Fluorescence Genetic modification Humans Neoplasms - genetics Neoplasms - therapy Oncolysis Oncolytic Virotherapy Oncolytic Viruses - genetics Real time Replication Virus Replication Viruses Visualization
Online-Zugang:	Volltext
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