Legionella pneumophila as a cause of cavitary lung disease in systemic lupus erythematous
Legionnaire’s disease (LD) is most commonly caused by Legionella pneumophila (L. pneumophila). In immunocompromised patients LD can cause necrosis of the lung parenchyma with abscess formation and cavitation. Systemic lupus erythematosus (SLE) is an autoimmune disorder with features of both primary...
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| Veröffentlicht in: | Lupus 2021-05, Vol.30 (6), p.1010-1012 |
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| creator | Khokher, Waleed Kesireddy, Nithin Adunse, Josephine Mudiyanselage, Prabath Herath Iftikhar, Saffa Assaly, Ragheb |
| description | Legionnaire’s disease (LD) is most commonly caused by Legionella pneumophila (L. pneumophila). In immunocompromised patients LD can cause necrosis of the lung parenchyma with abscess formation and cavitation. Systemic lupus erythematosus (SLE) is an autoimmune disorder with features of both primary and secondary immunodeficiency. SLE patients often develop pulmonary abnormalities, but rarely develop lung cavitations. We report a case of cavitary pneumonia caused by L. pneumophila in a 64-year-old female patient with SLE. We also highlight reasons why SLE patients are more prone to L. pneumophila infections. The importance of using correct diagnostic methods for recognizing and treating such infections is also discussed, as mistreatment of cavitary lesions in SLE patients with steroid therapy can have fatal outcomes as the infectious process can significantly worsen. |
| doi_str_mv | 10.1177/0961203321990102 |
| format | Article |
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In immunocompromised patients LD can cause necrosis of the lung parenchyma with abscess formation and cavitation. Systemic lupus erythematosus (SLE) is an autoimmune disorder with features of both primary and secondary immunodeficiency. SLE patients often develop pulmonary abnormalities, but rarely develop lung cavitations. We report a case of cavitary pneumonia caused by L. pneumophila in a 64-year-old female patient with SLE. We also highlight reasons why SLE patients are more prone to L. pneumophila infections. 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In immunocompromised patients LD can cause necrosis of the lung parenchyma with abscess formation and cavitation. Systemic lupus erythematosus (SLE) is an autoimmune disorder with features of both primary and secondary immunodeficiency. SLE patients often develop pulmonary abnormalities, but rarely develop lung cavitations. We report a case of cavitary pneumonia caused by L. pneumophila in a 64-year-old female patient with SLE. We also highlight reasons why SLE patients are more prone to L. pneumophila infections. The importance of using correct diagnostic methods for recognizing and treating such infections is also discussed, as mistreatment of cavitary lesions in SLE patients with steroid therapy can have fatal outcomes as the infectious process can significantly worsen.</description><subject>Case reports</subject><subject>Cavitation</subject><subject>Immunocompromised hosts</subject><subject>Immunodeficiency</subject><subject>Legionella pneumophila</subject><subject>Legionnaire's disease</subject><subject>Lung diseases</subject><subject>Lupus</subject><subject>Parenchyma</subject><subject>Systemic lupus erythematosus</subject><issn>0961-2033</issn><issn>1477-0962</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp1kMtLAzEQxoMotlbvnmTBi5fVPDbJ5ijFFxS86MHTkk1m25Tuw81G6H9vllaFgqcM-X7zzcyH0CXBt4RIeYeVIBQzRolSmGB6hKYkkzKN__QYTUc5HfUJOvN-jTFmRIlTNGEsU5JhPEUfC1i6toHNRiddA6Fuu5WLtfaJTowOHpK2isWXG3S_TTahWSbWedBRcE3it36A2pkodMEn0G-HFdR6aIM_RyeV3ni42L8z9P748DZ_ThevTy_z-0VqmOBDyim3FZcUl5XFpeHAic2lNEwSbYQEW1pDTZmXpVG5yTWTHDKZK8Oyigur2Azd7Hy7vv0M4Ieidt6MBzUQ1yholhMhmJJZRK8P0HUb-iZuV1BOqJAqz2ik8I4yfet9D1XR9a6O1xcEF2PsxWHsseVqbxzKGuxvw0_OEUh3gNdL-Jv6r-E3l0yKPQ</recordid><startdate>202105</startdate><enddate>202105</enddate><creator>Khokher, Waleed</creator><creator>Kesireddy, Nithin</creator><creator>Adunse, Josephine</creator><creator>Mudiyanselage, Prabath Herath</creator><creator>Iftikhar, Saffa</creator><creator>Assaly, Ragheb</creator><general>SAGE Publications</general><general>Sage Publications Ltd</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-9539-5583</orcidid></search><sort><creationdate>202105</creationdate><title>Legionella pneumophila as a cause of cavitary lung disease in systemic lupus erythematous</title><author>Khokher, Waleed ; Kesireddy, Nithin ; Adunse, Josephine ; Mudiyanselage, Prabath Herath ; Iftikhar, Saffa ; Assaly, Ragheb</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c365t-525df5720bfd0bc5e51d877c371ac67edbdc2cb8bbc98c8a375e4789c34f56d93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Case reports</topic><topic>Cavitation</topic><topic>Immunocompromised hosts</topic><topic>Immunodeficiency</topic><topic>Legionella pneumophila</topic><topic>Legionnaire's disease</topic><topic>Lung diseases</topic><topic>Lupus</topic><topic>Parenchyma</topic><topic>Systemic lupus erythematosus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Khokher, Waleed</creatorcontrib><creatorcontrib>Kesireddy, Nithin</creatorcontrib><creatorcontrib>Adunse, Josephine</creatorcontrib><creatorcontrib>Mudiyanselage, Prabath Herath</creatorcontrib><creatorcontrib>Iftikhar, Saffa</creatorcontrib><creatorcontrib>Assaly, Ragheb</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Lupus</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Khokher, Waleed</au><au>Kesireddy, Nithin</au><au>Adunse, Josephine</au><au>Mudiyanselage, Prabath Herath</au><au>Iftikhar, Saffa</au><au>Assaly, Ragheb</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Legionella pneumophila as a cause of cavitary lung disease in systemic lupus erythematous</atitle><jtitle>Lupus</jtitle><addtitle>Lupus</addtitle><date>2021-05</date><risdate>2021</risdate><volume>30</volume><issue>6</issue><spage>1010</spage><epage>1012</epage><pages>1010-1012</pages><issn>0961-2033</issn><eissn>1477-0962</eissn><abstract>Legionnaire’s disease (LD) is most commonly caused by Legionella pneumophila (L. pneumophila). 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| ispartof | Lupus, 2021-05, Vol.30 (6), p.1010-1012 |
| issn | 0961-2033 1477-0962 |
| language | eng |
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| source | SAGE Complete A-Z List |
| subjects | Case reports Cavitation Immunocompromised hosts Immunodeficiency Legionella pneumophila Legionnaire's disease Lung diseases Lupus Parenchyma Systemic lupus erythematosus |
| title | Legionella pneumophila as a cause of cavitary lung disease in systemic lupus erythematous |
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