Moderating effect of sense of coherence on the relationship between symptom distress and health-related quality of life in patients receiving cancer chemotherapy
Purpose This study is aimed at examining the buffering effect of sense of coherence (SOC) on symptom distress during cancer drug therapy, which thereby affects health-related quality of life (QoL), and obtaining suggestions for promoting supportive care. Methods We investigated health-related QoL (S...
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| Veröffentlicht in: | Supportive care in cancer 2021-08, Vol.29 (8), p.4651-4662 |
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| container_title | Supportive care in cancer |
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| creator | Asaba, Kaori Okawa, Akiko |
| description | Purpose
This study is aimed at examining the buffering effect of sense of coherence (SOC) on symptom distress during cancer drug therapy, which thereby affects health-related quality of life (QoL), and obtaining suggestions for promoting supportive care.
Methods
We investigated health-related QoL (SF-8), symptom distress (using the Symptom Distress Scale (SDS)), and SOC (the SOC 13-item Scale) in 66 patients receiving adjuvant chemotherapy for non-small cell lung cancer. We employed descriptive statistics to seek the correlation of each variable; then, a hierarchical multiple regression analysis was conducted with SF-8 score as the dependent variable.
Results
Results showed that significant changes in bodily pain showed a buffering effect on the SDS and sense of comprehensibility (
β
= − 0.658,
p
|
| doi_str_mv | 10.1007/s00520-021-06003-4 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_2481636742</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A666681880</galeid><sourcerecordid>A666681880</sourcerecordid><originalsourceid>FETCH-LOGICAL-c508t-458ddb1125241c5246c9a3fdd3885519c47dae6389e9405d18477eae320e3e333</originalsourceid><addsrcrecordid>eNp9ks1u1DAUhS0EokPhBVggS2y6SfFv4iyrCgpSERtYWx77ZuIqsVPbQzWPw5vidAoVCGFL_v3O8bV0EHpNyTklpHuXCZGMNITRhrSE8EY8QRsqOG86zvunaEN6QRvBpTxBL3K-IYR2nWTP0QnnktCW0Q368Tk6SKb4sMMwDGALjgPOEDKsCxtHSBBs3QRcRsAJpgrHkEe_4C2UO4CA82FeSpyx87kkyBmb4PAIZipjcy8Ah2_3ZvLlsJpOfgDsA16qE4SSq6kF_30twZr6VsJ2hDnW55JZDi_Rs8FMGV49zKfo24f3Xy8_Ntdfrj5dXlw3VhJVGiGVc1tKmWSC2jq0tjd8cI4rJSXtreicgZarHnpBpKNKdB0Y4IwAB875KTo7-i4p3u4hFz37bGGaTIC4z5oJRVvedoJV9O1f6E3cp1Cr00wKKbgifftI7cwE2ochlmTsaqov2toUVYpU6vwfVO0OZm9jgMHX8z8E7CiwKeacYNBL8rNJB02JXnOhj7nQNRf6PhdaVNGbh4r32xncb8mvIFSAH4Fcr8IO0uOX_mP7E2Ycw5o</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2545438096</pqid></control><display><type>article</type><title>Moderating effect of sense of coherence on the relationship between symptom distress and health-related quality of life in patients receiving cancer chemotherapy</title><source>SpringerLink Journals</source><creator>Asaba, Kaori ; Okawa, Akiko</creator><creatorcontrib>Asaba, Kaori ; Okawa, Akiko</creatorcontrib><description><![CDATA[Purpose
This study is aimed at examining the buffering effect of sense of coherence (SOC) on symptom distress during cancer drug therapy, which thereby affects health-related quality of life (QoL), and obtaining suggestions for promoting supportive care.
Methods
We investigated health-related QoL (SF-8), symptom distress (using the Symptom Distress Scale (SDS)), and SOC (the SOC 13-item Scale) in 66 patients receiving adjuvant chemotherapy for non-small cell lung cancer. We employed descriptive statistics to seek the correlation of each variable; then, a hierarchical multiple regression analysis was conducted with SF-8 score as the dependent variable.
Results
Results showed that significant changes in bodily pain showed a buffering effect on the SDS and sense of comprehensibility (
β
= − 0.658,
p
< 0.01,
β
= − 0.319,
p
< 0.05), sense of manageability (
β
= − 0.658,
p
< 0.01,
β
= 0.398,
p
< 0.01), and meaningfulness (
β
= − 0.658,
p
< 0.01,
β
= − 0.257,
p
< 0.05). Significant changes in general health perception showed a buffering effect on the SDS and sense of manageability (
β
= − 0.406,
p
< 0.01,
β
= 0.329,
p
< 0.05). As a result of the simple inclination test, SOC proved to be effective under high levels of symptom distress; the buffering effect of sense of manageability was reversed regarding bodily pain; and when meaningfulness was lower, it had a positive effect on QoL.
Conclusion
This study revealed that SOC exerts a buffering effect in situations where symptoms are highly painful. It also revealed that the effect of SOC was reversed for bodily pain and that a high SOC had a negative effect on QoL.]]></description><identifier>ISSN: 0941-4355</identifier><identifier>EISSN: 1433-7339</identifier><identifier>DOI: 10.1007/s00520-021-06003-4</identifier><identifier>PMID: 33501621</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Analysis ; Antimitotic agents ; Antineoplastic agents ; Cancer ; Cancer patients ; Chemotherapy ; Health ; Health aspects ; Lung cancer ; Lung cancer, Non-small cell ; Medicine ; Medicine & Public Health ; Nursing ; Nursing Research ; Oncology ; Original Article ; Pain ; Pain Medicine ; Quality of life ; Rehabilitation Medicine</subject><ispartof>Supportive care in cancer, 2021-08, Vol.29 (8), p.4651-4662</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature 2021</rights><rights>COPYRIGHT 2021 Springer</rights><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c508t-458ddb1125241c5246c9a3fdd3885519c47dae6389e9405d18477eae320e3e333</citedby><cites>FETCH-LOGICAL-c508t-458ddb1125241c5246c9a3fdd3885519c47dae6389e9405d18477eae320e3e333</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00520-021-06003-4$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00520-021-06003-4$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33501621$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Asaba, Kaori</creatorcontrib><creatorcontrib>Okawa, Akiko</creatorcontrib><title>Moderating effect of sense of coherence on the relationship between symptom distress and health-related quality of life in patients receiving cancer chemotherapy</title><title>Supportive care in cancer</title><addtitle>Support Care Cancer</addtitle><addtitle>Support Care Cancer</addtitle><description><![CDATA[Purpose
This study is aimed at examining the buffering effect of sense of coherence (SOC) on symptom distress during cancer drug therapy, which thereby affects health-related quality of life (QoL), and obtaining suggestions for promoting supportive care.
Methods
We investigated health-related QoL (SF-8), symptom distress (using the Symptom Distress Scale (SDS)), and SOC (the SOC 13-item Scale) in 66 patients receiving adjuvant chemotherapy for non-small cell lung cancer. We employed descriptive statistics to seek the correlation of each variable; then, a hierarchical multiple regression analysis was conducted with SF-8 score as the dependent variable.
Results
Results showed that significant changes in bodily pain showed a buffering effect on the SDS and sense of comprehensibility (
β
= − 0.658,
p
< 0.01,
β
= − 0.319,
p
< 0.05), sense of manageability (
β
= − 0.658,
p
< 0.01,
β
= 0.398,
p
< 0.01), and meaningfulness (
β
= − 0.658,
p
< 0.01,
β
= − 0.257,
p
< 0.05). Significant changes in general health perception showed a buffering effect on the SDS and sense of manageability (
β
= − 0.406,
p
< 0.01,
β
= 0.329,
p
< 0.05). As a result of the simple inclination test, SOC proved to be effective under high levels of symptom distress; the buffering effect of sense of manageability was reversed regarding bodily pain; and when meaningfulness was lower, it had a positive effect on QoL.
Conclusion
This study revealed that SOC exerts a buffering effect in situations where symptoms are highly painful. It also revealed that the effect of SOC was reversed for bodily pain and that a high SOC had a negative effect on QoL.]]></description><subject>Analysis</subject><subject>Antimitotic agents</subject><subject>Antineoplastic agents</subject><subject>Cancer</subject><subject>Cancer patients</subject><subject>Chemotherapy</subject><subject>Health</subject><subject>Health aspects</subject><subject>Lung cancer</subject><subject>Lung cancer, Non-small cell</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Nursing</subject><subject>Nursing Research</subject><subject>Oncology</subject><subject>Original Article</subject><subject>Pain</subject><subject>Pain Medicine</subject><subject>Quality of life</subject><subject>Rehabilitation Medicine</subject><issn>0941-4355</issn><issn>1433-7339</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNp9ks1u1DAUhS0EokPhBVggS2y6SfFv4iyrCgpSERtYWx77ZuIqsVPbQzWPw5vidAoVCGFL_v3O8bV0EHpNyTklpHuXCZGMNITRhrSE8EY8QRsqOG86zvunaEN6QRvBpTxBL3K-IYR2nWTP0QnnktCW0Q368Tk6SKb4sMMwDGALjgPOEDKsCxtHSBBs3QRcRsAJpgrHkEe_4C2UO4CA82FeSpyx87kkyBmb4PAIZipjcy8Ah2_3ZvLlsJpOfgDsA16qE4SSq6kF_30twZr6VsJ2hDnW55JZDi_Rs8FMGV49zKfo24f3Xy8_Ntdfrj5dXlw3VhJVGiGVc1tKmWSC2jq0tjd8cI4rJSXtreicgZarHnpBpKNKdB0Y4IwAB875KTo7-i4p3u4hFz37bGGaTIC4z5oJRVvedoJV9O1f6E3cp1Cr00wKKbgifftI7cwE2ochlmTsaqov2toUVYpU6vwfVO0OZm9jgMHX8z8E7CiwKeacYNBL8rNJB02JXnOhj7nQNRf6PhdaVNGbh4r32xncb8mvIFSAH4Fcr8IO0uOX_mP7E2Ycw5o</recordid><startdate>20210801</startdate><enddate>20210801</enddate><creator>Asaba, Kaori</creator><creator>Okawa, Akiko</creator><general>Springer Berlin Heidelberg</general><general>Springer</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88J</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HEHIP</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2R</scope><scope>M2S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20210801</creationdate><title>Moderating effect of sense of coherence on the relationship between symptom distress and health-related quality of life in patients receiving cancer chemotherapy</title><author>Asaba, Kaori ; Okawa, Akiko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c508t-458ddb1125241c5246c9a3fdd3885519c47dae6389e9405d18477eae320e3e333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Analysis</topic><topic>Antimitotic agents</topic><topic>Antineoplastic agents</topic><topic>Cancer</topic><topic>Cancer patients</topic><topic>Chemotherapy</topic><topic>Health</topic><topic>Health aspects</topic><topic>Lung cancer</topic><topic>Lung cancer, Non-small cell</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Nursing</topic><topic>Nursing Research</topic><topic>Oncology</topic><topic>Original Article</topic><topic>Pain</topic><topic>Pain Medicine</topic><topic>Quality of life</topic><topic>Rehabilitation Medicine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Asaba, Kaori</creatorcontrib><creatorcontrib>Okawa, Akiko</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Sociology Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Social Science Database</collection><collection>Sociology Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Supportive care in cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Asaba, Kaori</au><au>Okawa, Akiko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Moderating effect of sense of coherence on the relationship between symptom distress and health-related quality of life in patients receiving cancer chemotherapy</atitle><jtitle>Supportive care in cancer</jtitle><stitle>Support Care Cancer</stitle><addtitle>Support Care Cancer</addtitle><date>2021-08-01</date><risdate>2021</risdate><volume>29</volume><issue>8</issue><spage>4651</spage><epage>4662</epage><pages>4651-4662</pages><issn>0941-4355</issn><eissn>1433-7339</eissn><abstract><![CDATA[Purpose
This study is aimed at examining the buffering effect of sense of coherence (SOC) on symptom distress during cancer drug therapy, which thereby affects health-related quality of life (QoL), and obtaining suggestions for promoting supportive care.
Methods
We investigated health-related QoL (SF-8), symptom distress (using the Symptom Distress Scale (SDS)), and SOC (the SOC 13-item Scale) in 66 patients receiving adjuvant chemotherapy for non-small cell lung cancer. We employed descriptive statistics to seek the correlation of each variable; then, a hierarchical multiple regression analysis was conducted with SF-8 score as the dependent variable.
Results
Results showed that significant changes in bodily pain showed a buffering effect on the SDS and sense of comprehensibility (
β
= − 0.658,
p
< 0.01,
β
= − 0.319,
p
< 0.05), sense of manageability (
β
= − 0.658,
p
< 0.01,
β
= 0.398,
p
< 0.01), and meaningfulness (
β
= − 0.658,
p
< 0.01,
β
= − 0.257,
p
< 0.05). Significant changes in general health perception showed a buffering effect on the SDS and sense of manageability (
β
= − 0.406,
p
< 0.01,
β
= 0.329,
p
< 0.05). As a result of the simple inclination test, SOC proved to be effective under high levels of symptom distress; the buffering effect of sense of manageability was reversed regarding bodily pain; and when meaningfulness was lower, it had a positive effect on QoL.
Conclusion
This study revealed that SOC exerts a buffering effect in situations where symptoms are highly painful. It also revealed that the effect of SOC was reversed for bodily pain and that a high SOC had a negative effect on QoL.]]></abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>33501621</pmid><doi>10.1007/s00520-021-06003-4</doi><tpages>12</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0941-4355 |
| ispartof | Supportive care in cancer, 2021-08, Vol.29 (8), p.4651-4662 |
| issn | 0941-4355 1433-7339 |
| language | eng |
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| source | SpringerLink Journals |
| subjects | Analysis Antimitotic agents Antineoplastic agents Cancer Cancer patients Chemotherapy Health Health aspects Lung cancer Lung cancer, Non-small cell Medicine Medicine & Public Health Nursing Nursing Research Oncology Original Article Pain Pain Medicine Quality of life Rehabilitation Medicine |
| title | Moderating effect of sense of coherence on the relationship between symptom distress and health-related quality of life in patients receiving cancer chemotherapy |
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