Metabolic Effects of Recurrent Genetic Aberrations in Multiple Myeloma

Oncogene activation and malignant transformation exerts energetic, biosynthetic and redox demands on cancer cells due to increased proliferation, cell growth and tumor microenvironment adaptation. As such, altered metabolism is a hallmark of cancer, which is characterized by the reprogramming of mul...

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Veröffentlicht in:	Cancers 2021-01, Vol.13 (3), p.396
Hauptverfasser:	Bloedjes, Timon A, de Wilde, Guus, Guikema, Jeroen E J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Antibodies Antigens Asymptomatic Biosynthesis Bone marrow Cancer Cell differentiation Cell proliferation Chromosome aberrations Chromosome rearrangements Chromosome translocations Chromosomes Cyclin D1 Enzymes Fatty acids Fibroblast growth factor receptors Genetic transformation Glucose Immunoglobulins Kinases Lymphocytes B Metabolic pathways Metabolism Multiple myeloma Mutation Myc protein Plasma Proteins Review Transcription factors Tumor microenvironment
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