Label-free cell phenotypic study of opioid receptors and discovery of novel mu opioid ligands from natural products

Mu opioid receptor (MOR) is mainly a drug target for analgesia. Opioid-like agonists such as morphine have been clinically used for analgesia but have potential adverse effects. MOR antagonists have been demonstrated to alleviate these side effects. Plants (Carthamus tinctorius L, Cynanchum otophyll...

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Veröffentlicht in:	Journal of ethnopharmacology 2021-04, Vol.270, p.113872-113872, Article 113872
Hauptverfasser:	Hou, Tao, Xu, Fangfang, Peng, Xingrong, Zhou, Han, Zhang, Xiuli, Qiu, Minghua, Wang, Jixia, Liu, Yanfang, Liang, Xinmiao
Format:	Artikel
Sprache:	eng
Schlagworte:	Antagonist Dynamic mass redistribution Natural products Opioid receptors Selectivity
Online-Zugang:	Volltext
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