Effects of hyaluronic acid and deproteinized bovine bone mineral with 10% collagen for ridge preservation in compromised extraction sockets
Background The aim of this study was to evaluate the efficacy of deproteinized bovine bone mineral with 10% collagen (DBBM‐C) soaked with hyaluronic acid (HA) for ridge preservation in compromised extraction sockets. Methods Bilateral third, fourth premolars and first molar were hemisected, distal r...
Gespeichert in:
| Veröffentlicht in: | Journal of periodontology (1970) 2021-11, Vol.92 (11), p.1564-1575 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1575 |
|---|---|
| container_issue | 11 |
| container_start_page | 1564 |
| container_title | Journal of periodontology (1970) |
| container_volume | 92 |
| creator | Lee, Jun‐Beom Chu, Seoyoon Ben Amara, Heithem Song, Hyun‐Young Son, Min‐Jung Lee, Jungwon Kim, Hae‐Young Koo, Ki‐Tae Rhyu, In‐Chul |
| description | Background
The aim of this study was to evaluate the efficacy of deproteinized bovine bone mineral with 10% collagen (DBBM‐C) soaked with hyaluronic acid (HA) for ridge preservation in compromised extraction sockets.
Methods
Bilateral third, fourth premolars and first molar were hemisected, distal roots were extracted, and then combined endodontic periodontal lesion was induced in the remaining mesial roots. After 4 months, the mesial roots were extracted and the following four treatments were randomly performed: Absorbable collagen sponge (ACS), ACS soaked with HA (ACS+HA), ridge preservation with DBBM‐C covered with a collagen membrane (RP), ridge preservation with DBBM‐C mixed with HA and covered with a collagen membrane (RP+HA). Animals were sacrificed at 1 and 3 months following treatment. Ridge dimensional changes and bone formation were examined using microcomputed tomography, histology, and histomorphometry.
Results
At 1 month, ridge width was significantly higher in the RP and RP+HA groups than in the ACS and ACS+HA groups, while the highest proportion of mineralized bone was observed in ACS+HA group. At 3 months, ridge width remained significantly higher in the RP and RP+HA groups than in the ACS and ACS+HA groups. ACS+HA and RP+HA treatments featured the highest proportion of mineralized bone and bone volume density compared with the other groups. No statistical difference was observed between ACS+HA and RP+HA treatments.
Conclusions
Ridge preservation with the mixture DBBM‐C/HA prevented dimensional shrinkage and improved bone formation in compromised extraction sockets at 1 and 3 months. |
| doi_str_mv | 10.1002/JPER.20-0832 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2480450787</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2480450787</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3356-f61c0c97b53cbc0c4a4f50ded4f8e6bcd6ad97961a8b1c29bd44c335de68dafc3</originalsourceid><addsrcrecordid>eNp9kElPwzAQhS0EomW5cUa-IHEgYMeukxxRVTZVAiE4R449bg1JXOwUKH-BP427wJHLLJpvnp4eQkeUnFNC0ou7h9HjeUoSkrN0C_VpwVnCREa2UT-e04TxIu2hvRBe4ko5I7uoxxjPORWkj75HxoDqAnYGTxeynnvXWoWlshrLVmMNM-86sK39Ao0r925biC2WJk5e1vjDdlNMyQlWrq7lBFpsnMfe6gngmYcA_l121rXYthFpolxjQ9SCz85LtboEp16hCwdox8g6wOGm76Pnq9HT8CYZ31_fDi_HiWJsIBIjqCKqyKoBU1WcuORmQDRobnIQldJC6iIrBJV5RVVaVJrz5acGkWtpFNtHp2vd6OVtDqEroyMF0X0Lbh7KlOeED0iWZxE9W6PKuxA8mHLmbSP9oqSkXMZfLuMvU1Iu44_48UZ5XjWg_-DfvCPA1sCHrWHxr9hqoSRjgv0ADl6TMQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2480450787</pqid></control><display><type>article</type><title>Effects of hyaluronic acid and deproteinized bovine bone mineral with 10% collagen for ridge preservation in compromised extraction sockets</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Lee, Jun‐Beom ; Chu, Seoyoon ; Ben Amara, Heithem ; Song, Hyun‐Young ; Son, Min‐Jung ; Lee, Jungwon ; Kim, Hae‐Young ; Koo, Ki‐Tae ; Rhyu, In‐Chul</creator><creatorcontrib>Lee, Jun‐Beom ; Chu, Seoyoon ; Ben Amara, Heithem ; Song, Hyun‐Young ; Son, Min‐Jung ; Lee, Jungwon ; Kim, Hae‐Young ; Koo, Ki‐Tae ; Rhyu, In‐Chul</creatorcontrib><description>Background
The aim of this study was to evaluate the efficacy of deproteinized bovine bone mineral with 10% collagen (DBBM‐C) soaked with hyaluronic acid (HA) for ridge preservation in compromised extraction sockets.
Methods
Bilateral third, fourth premolars and first molar were hemisected, distal roots were extracted, and then combined endodontic periodontal lesion was induced in the remaining mesial roots. After 4 months, the mesial roots were extracted and the following four treatments were randomly performed: Absorbable collagen sponge (ACS), ACS soaked with HA (ACS+HA), ridge preservation with DBBM‐C covered with a collagen membrane (RP), ridge preservation with DBBM‐C mixed with HA and covered with a collagen membrane (RP+HA). Animals were sacrificed at 1 and 3 months following treatment. Ridge dimensional changes and bone formation were examined using microcomputed tomography, histology, and histomorphometry.
Results
At 1 month, ridge width was significantly higher in the RP and RP+HA groups than in the ACS and ACS+HA groups, while the highest proportion of mineralized bone was observed in ACS+HA group. At 3 months, ridge width remained significantly higher in the RP and RP+HA groups than in the ACS and ACS+HA groups. ACS+HA and RP+HA treatments featured the highest proportion of mineralized bone and bone volume density compared with the other groups. No statistical difference was observed between ACS+HA and RP+HA treatments.
Conclusions
Ridge preservation with the mixture DBBM‐C/HA prevented dimensional shrinkage and improved bone formation in compromised extraction sockets at 1 and 3 months.</description><identifier>ISSN: 0022-3492</identifier><identifier>EISSN: 1943-3670</identifier><identifier>DOI: 10.1002/JPER.20-0832</identifier><identifier>PMID: 33484160</identifier><language>eng</language><publisher>United States</publisher><subject>alveolar bone grafting ; Alveolar Bone Loss - prevention & control ; Alveolar Bone Loss - surgery ; Alveolar Ridge Augmentation ; Animals ; bone regeneration ; Bone Substitutes - therapeutic use ; Cattle ; Collagen ; growth factors ; hyaluronic acid ; Hyaluronic Acid - therapeutic use ; Minerals - therapeutic use ; Tooth Extraction ; tooth socket ; Tooth Socket - surgery ; X-Ray Microtomography</subject><ispartof>Journal of periodontology (1970), 2021-11, Vol.92 (11), p.1564-1575</ispartof><rights>2021 American Academy of Periodontology</rights><rights>2021 American Academy of Periodontology.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3356-f61c0c97b53cbc0c4a4f50ded4f8e6bcd6ad97961a8b1c29bd44c335de68dafc3</citedby><cites>FETCH-LOGICAL-c3356-f61c0c97b53cbc0c4a4f50ded4f8e6bcd6ad97961a8b1c29bd44c335de68dafc3</cites><orcidid>0000-0002-9809-2630 ; 0000-0002-7927-9838 ; 0000-0002-5508-442X ; 0000-0003-4110-6381 ; 0000-0002-5571-118X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2FJPER.20-0832$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2FJPER.20-0832$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33484160$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Jun‐Beom</creatorcontrib><creatorcontrib>Chu, Seoyoon</creatorcontrib><creatorcontrib>Ben Amara, Heithem</creatorcontrib><creatorcontrib>Song, Hyun‐Young</creatorcontrib><creatorcontrib>Son, Min‐Jung</creatorcontrib><creatorcontrib>Lee, Jungwon</creatorcontrib><creatorcontrib>Kim, Hae‐Young</creatorcontrib><creatorcontrib>Koo, Ki‐Tae</creatorcontrib><creatorcontrib>Rhyu, In‐Chul</creatorcontrib><title>Effects of hyaluronic acid and deproteinized bovine bone mineral with 10% collagen for ridge preservation in compromised extraction sockets</title><title>Journal of periodontology (1970)</title><addtitle>J Periodontol</addtitle><description>Background
The aim of this study was to evaluate the efficacy of deproteinized bovine bone mineral with 10% collagen (DBBM‐C) soaked with hyaluronic acid (HA) for ridge preservation in compromised extraction sockets.
Methods
Bilateral third, fourth premolars and first molar were hemisected, distal roots were extracted, and then combined endodontic periodontal lesion was induced in the remaining mesial roots. After 4 months, the mesial roots were extracted and the following four treatments were randomly performed: Absorbable collagen sponge (ACS), ACS soaked with HA (ACS+HA), ridge preservation with DBBM‐C covered with a collagen membrane (RP), ridge preservation with DBBM‐C mixed with HA and covered with a collagen membrane (RP+HA). Animals were sacrificed at 1 and 3 months following treatment. Ridge dimensional changes and bone formation were examined using microcomputed tomography, histology, and histomorphometry.
Results
At 1 month, ridge width was significantly higher in the RP and RP+HA groups than in the ACS and ACS+HA groups, while the highest proportion of mineralized bone was observed in ACS+HA group. At 3 months, ridge width remained significantly higher in the RP and RP+HA groups than in the ACS and ACS+HA groups. ACS+HA and RP+HA treatments featured the highest proportion of mineralized bone and bone volume density compared with the other groups. No statistical difference was observed between ACS+HA and RP+HA treatments.
Conclusions
Ridge preservation with the mixture DBBM‐C/HA prevented dimensional shrinkage and improved bone formation in compromised extraction sockets at 1 and 3 months.</description><subject>alveolar bone grafting</subject><subject>Alveolar Bone Loss - prevention & control</subject><subject>Alveolar Bone Loss - surgery</subject><subject>Alveolar Ridge Augmentation</subject><subject>Animals</subject><subject>bone regeneration</subject><subject>Bone Substitutes - therapeutic use</subject><subject>Cattle</subject><subject>Collagen</subject><subject>growth factors</subject><subject>hyaluronic acid</subject><subject>Hyaluronic Acid - therapeutic use</subject><subject>Minerals - therapeutic use</subject><subject>Tooth Extraction</subject><subject>tooth socket</subject><subject>Tooth Socket - surgery</subject><subject>X-Ray Microtomography</subject><issn>0022-3492</issn><issn>1943-3670</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kElPwzAQhS0EomW5cUa-IHEgYMeukxxRVTZVAiE4R449bg1JXOwUKH-BP427wJHLLJpvnp4eQkeUnFNC0ou7h9HjeUoSkrN0C_VpwVnCREa2UT-e04TxIu2hvRBe4ko5I7uoxxjPORWkj75HxoDqAnYGTxeynnvXWoWlshrLVmMNM-86sK39Ao0r925biC2WJk5e1vjDdlNMyQlWrq7lBFpsnMfe6gngmYcA_l121rXYthFpolxjQ9SCz85LtboEp16hCwdox8g6wOGm76Pnq9HT8CYZ31_fDi_HiWJsIBIjqCKqyKoBU1WcuORmQDRobnIQldJC6iIrBJV5RVVaVJrz5acGkWtpFNtHp2vd6OVtDqEroyMF0X0Lbh7KlOeED0iWZxE9W6PKuxA8mHLmbSP9oqSkXMZfLuMvU1Iu44_48UZ5XjWg_-DfvCPA1sCHrWHxr9hqoSRjgv0ADl6TMQ</recordid><startdate>202111</startdate><enddate>202111</enddate><creator>Lee, Jun‐Beom</creator><creator>Chu, Seoyoon</creator><creator>Ben Amara, Heithem</creator><creator>Song, Hyun‐Young</creator><creator>Son, Min‐Jung</creator><creator>Lee, Jungwon</creator><creator>Kim, Hae‐Young</creator><creator>Koo, Ki‐Tae</creator><creator>Rhyu, In‐Chul</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-9809-2630</orcidid><orcidid>https://orcid.org/0000-0002-7927-9838</orcidid><orcidid>https://orcid.org/0000-0002-5508-442X</orcidid><orcidid>https://orcid.org/0000-0003-4110-6381</orcidid><orcidid>https://orcid.org/0000-0002-5571-118X</orcidid></search><sort><creationdate>202111</creationdate><title>Effects of hyaluronic acid and deproteinized bovine bone mineral with 10% collagen for ridge preservation in compromised extraction sockets</title><author>Lee, Jun‐Beom ; Chu, Seoyoon ; Ben Amara, Heithem ; Song, Hyun‐Young ; Son, Min‐Jung ; Lee, Jungwon ; Kim, Hae‐Young ; Koo, Ki‐Tae ; Rhyu, In‐Chul</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3356-f61c0c97b53cbc0c4a4f50ded4f8e6bcd6ad97961a8b1c29bd44c335de68dafc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>alveolar bone grafting</topic><topic>Alveolar Bone Loss - prevention & control</topic><topic>Alveolar Bone Loss - surgery</topic><topic>Alveolar Ridge Augmentation</topic><topic>Animals</topic><topic>bone regeneration</topic><topic>Bone Substitutes - therapeutic use</topic><topic>Cattle</topic><topic>Collagen</topic><topic>growth factors</topic><topic>hyaluronic acid</topic><topic>Hyaluronic Acid - therapeutic use</topic><topic>Minerals - therapeutic use</topic><topic>Tooth Extraction</topic><topic>tooth socket</topic><topic>Tooth Socket - surgery</topic><topic>X-Ray Microtomography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Jun‐Beom</creatorcontrib><creatorcontrib>Chu, Seoyoon</creatorcontrib><creatorcontrib>Ben Amara, Heithem</creatorcontrib><creatorcontrib>Song, Hyun‐Young</creatorcontrib><creatorcontrib>Son, Min‐Jung</creatorcontrib><creatorcontrib>Lee, Jungwon</creatorcontrib><creatorcontrib>Kim, Hae‐Young</creatorcontrib><creatorcontrib>Koo, Ki‐Tae</creatorcontrib><creatorcontrib>Rhyu, In‐Chul</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of periodontology (1970)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Jun‐Beom</au><au>Chu, Seoyoon</au><au>Ben Amara, Heithem</au><au>Song, Hyun‐Young</au><au>Son, Min‐Jung</au><au>Lee, Jungwon</au><au>Kim, Hae‐Young</au><au>Koo, Ki‐Tae</au><au>Rhyu, In‐Chul</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of hyaluronic acid and deproteinized bovine bone mineral with 10% collagen for ridge preservation in compromised extraction sockets</atitle><jtitle>Journal of periodontology (1970)</jtitle><addtitle>J Periodontol</addtitle><date>2021-11</date><risdate>2021</risdate><volume>92</volume><issue>11</issue><spage>1564</spage><epage>1575</epage><pages>1564-1575</pages><issn>0022-3492</issn><eissn>1943-3670</eissn><abstract>Background
The aim of this study was to evaluate the efficacy of deproteinized bovine bone mineral with 10% collagen (DBBM‐C) soaked with hyaluronic acid (HA) for ridge preservation in compromised extraction sockets.
Methods
Bilateral third, fourth premolars and first molar were hemisected, distal roots were extracted, and then combined endodontic periodontal lesion was induced in the remaining mesial roots. After 4 months, the mesial roots were extracted and the following four treatments were randomly performed: Absorbable collagen sponge (ACS), ACS soaked with HA (ACS+HA), ridge preservation with DBBM‐C covered with a collagen membrane (RP), ridge preservation with DBBM‐C mixed with HA and covered with a collagen membrane (RP+HA). Animals were sacrificed at 1 and 3 months following treatment. Ridge dimensional changes and bone formation were examined using microcomputed tomography, histology, and histomorphometry.
Results
At 1 month, ridge width was significantly higher in the RP and RP+HA groups than in the ACS and ACS+HA groups, while the highest proportion of mineralized bone was observed in ACS+HA group. At 3 months, ridge width remained significantly higher in the RP and RP+HA groups than in the ACS and ACS+HA groups. ACS+HA and RP+HA treatments featured the highest proportion of mineralized bone and bone volume density compared with the other groups. No statistical difference was observed between ACS+HA and RP+HA treatments.
Conclusions
Ridge preservation with the mixture DBBM‐C/HA prevented dimensional shrinkage and improved bone formation in compromised extraction sockets at 1 and 3 months.</abstract><cop>United States</cop><pmid>33484160</pmid><doi>10.1002/JPER.20-0832</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0002-9809-2630</orcidid><orcidid>https://orcid.org/0000-0002-7927-9838</orcidid><orcidid>https://orcid.org/0000-0002-5508-442X</orcidid><orcidid>https://orcid.org/0000-0003-4110-6381</orcidid><orcidid>https://orcid.org/0000-0002-5571-118X</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3492 |
| ispartof | Journal of periodontology (1970), 2021-11, Vol.92 (11), p.1564-1575 |
| issn | 0022-3492 1943-3670 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2480450787 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | alveolar bone grafting Alveolar Bone Loss - prevention & control Alveolar Bone Loss - surgery Alveolar Ridge Augmentation Animals bone regeneration Bone Substitutes - therapeutic use Cattle Collagen growth factors hyaluronic acid Hyaluronic Acid - therapeutic use Minerals - therapeutic use Tooth Extraction tooth socket Tooth Socket - surgery X-Ray Microtomography |
| title | Effects of hyaluronic acid and deproteinized bovine bone mineral with 10% collagen for ridge preservation in compromised extraction sockets |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T06%3A43%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effects%20of%20hyaluronic%20acid%20and%20deproteinized%20bovine%20bone%20mineral%20with%2010%25%20collagen%20for%20ridge%20preservation%20in%20compromised%20extraction%20sockets&rft.jtitle=Journal%20of%20periodontology%20(1970)&rft.au=Lee,%20Jun%E2%80%90Beom&rft.date=2021-11&rft.volume=92&rft.issue=11&rft.spage=1564&rft.epage=1575&rft.pages=1564-1575&rft.issn=0022-3492&rft.eissn=1943-3670&rft_id=info:doi/10.1002/JPER.20-0832&rft_dat=%3Cproquest_cross%3E2480450787%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2480450787&rft_id=info:pmid/33484160&rfr_iscdi=true |