Enhancing cyst-like lesions of the white matter in tuberous sclerosis complex: a novel neuroradiological finding
Tuberous sclerosis complex (TSC) is an autosomal dominant condition clinically presenting with heterogenous clinical features. Multiple neuroradiological manifestations have been associated with TSC, such as tubers, radial migration lines, subependymal nodules, subependymal giant cell astrocytomas,...
Gespeichert in:
| Veröffentlicht in: | Neuroradiology 2021-06, Vol.63 (6), p.971-974 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 974 |
|---|---|
| container_issue | 6 |
| container_start_page | 971 |
| container_title | Neuroradiology |
| container_volume | 63 |
| creator | D’Amico, Alessandra Perillo, Teresa Russo, Carmela Ugga, Lorenzo Melis, Daniela Santoro, Claudia Piluso, Giulio Cinalli, Giuseppe |
| description | Tuberous sclerosis complex (TSC) is an autosomal dominant condition clinically presenting with heterogenous clinical features. Multiple neuroradiological manifestations have been associated with TSC, such as tubers, radial migration lines, subependymal nodules, subependymal giant cell astrocytomas, and cyst-like lesions of the white matter (CLLWMs). The latter have been described as non-enhancing well-defined cysts whose pathogenesis is still unknown. We describe 2 TSC patients with CLLWM showing contrast enhancement after Gadolinium injection, a previously unreported entity. |
| doi_str_mv | 10.1007/s00234-021-02647-5 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2480298420</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2480298420</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-6a03da21ce93985b1e05ad05d0c789e537011fb3a80c1c06199bfb4a22f270603</originalsourceid><addsrcrecordid>eNp9kcFO3DAQhq2qFWy3vEAPyFIvvQTGdrJOuKHVtiCtxKU9W44z2TV17MVOoLw93i4FiQOH8Yw03_wz1k_IVwZnDECeJwAuygI4y7EoZVF9IDNWCl6whsNHMsv9uhBNCcfkc0q3ACCkkEfkWIiyZiBhRnYrv9XeWL-h5jGNhbN_kDpMNvhEQ0_HLdKHrR2RDnocMVLr6Ti1GMOUaDIuF8kmasKwc_j3gmrqwz066nGKIerOBhc21mhHe-u7vOYL-dRrl_DkOc_J7x-rX8urYn3z83p5uS6MkNVYLDSITnNmsBFNXbUModIdVB0YWTdYCQmM9a3QNRhmYMGapu3bUnPecwkLEHPy_aC7i-FuwjSqwSaDzmmP-XbFyxp4U5d8j357g96GKfp8neIVrwWT-ckUP1AmfzlF7NUu2kHHR8VA7f1QBz9U9kP980NVeej0WXpqB-xeRv4bkAFxAFJu-Q3G193vyD4Bm3GWBQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2528317283</pqid></control><display><type>article</type><title>Enhancing cyst-like lesions of the white matter in tuberous sclerosis complex: a novel neuroradiological finding</title><source>SpringerLink Journals - AutoHoldings</source><creator>D’Amico, Alessandra ; Perillo, Teresa ; Russo, Carmela ; Ugga, Lorenzo ; Melis, Daniela ; Santoro, Claudia ; Piluso, Giulio ; Cinalli, Giuseppe</creator><creatorcontrib>D’Amico, Alessandra ; Perillo, Teresa ; Russo, Carmela ; Ugga, Lorenzo ; Melis, Daniela ; Santoro, Claudia ; Piluso, Giulio ; Cinalli, Giuseppe</creatorcontrib><description>Tuberous sclerosis complex (TSC) is an autosomal dominant condition clinically presenting with heterogenous clinical features. Multiple neuroradiological manifestations have been associated with TSC, such as tubers, radial migration lines, subependymal nodules, subependymal giant cell astrocytomas, and cyst-like lesions of the white matter (CLLWMs). The latter have been described as non-enhancing well-defined cysts whose pathogenesis is still unknown. We describe 2 TSC patients with CLLWM showing contrast enhancement after Gadolinium injection, a previously unreported entity.</description><identifier>ISSN: 0028-3940</identifier><identifier>EISSN: 1432-1920</identifier><identifier>DOI: 10.1007/s00234-021-02647-5</identifier><identifier>PMID: 33481070</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Astrocytoma ; Cysts ; Gadolinium ; Imaging ; Lesions ; Medicine ; Medicine & Public Health ; Neurology ; Neuroradiology ; Neurosciences ; Neurosurgery ; Nodules ; Pathogenesis ; Radiology ; Short Report ; Substantia alba ; Tuberous sclerosis</subject><ispartof>Neuroradiology, 2021-06, Vol.63 (6), p.971-974</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature 2021</rights><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-6a03da21ce93985b1e05ad05d0c789e537011fb3a80c1c06199bfb4a22f270603</citedby><cites>FETCH-LOGICAL-c375t-6a03da21ce93985b1e05ad05d0c789e537011fb3a80c1c06199bfb4a22f270603</cites><orcidid>0000-0002-3840-7637</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00234-021-02647-5$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00234-021-02647-5$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33481070$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>D’Amico, Alessandra</creatorcontrib><creatorcontrib>Perillo, Teresa</creatorcontrib><creatorcontrib>Russo, Carmela</creatorcontrib><creatorcontrib>Ugga, Lorenzo</creatorcontrib><creatorcontrib>Melis, Daniela</creatorcontrib><creatorcontrib>Santoro, Claudia</creatorcontrib><creatorcontrib>Piluso, Giulio</creatorcontrib><creatorcontrib>Cinalli, Giuseppe</creatorcontrib><title>Enhancing cyst-like lesions of the white matter in tuberous sclerosis complex: a novel neuroradiological finding</title><title>Neuroradiology</title><addtitle>Neuroradiology</addtitle><addtitle>Neuroradiology</addtitle><description>Tuberous sclerosis complex (TSC) is an autosomal dominant condition clinically presenting with heterogenous clinical features. Multiple neuroradiological manifestations have been associated with TSC, such as tubers, radial migration lines, subependymal nodules, subependymal giant cell astrocytomas, and cyst-like lesions of the white matter (CLLWMs). The latter have been described as non-enhancing well-defined cysts whose pathogenesis is still unknown. We describe 2 TSC patients with CLLWM showing contrast enhancement after Gadolinium injection, a previously unreported entity.</description><subject>Astrocytoma</subject><subject>Cysts</subject><subject>Gadolinium</subject><subject>Imaging</subject><subject>Lesions</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Neurology</subject><subject>Neuroradiology</subject><subject>Neurosciences</subject><subject>Neurosurgery</subject><subject>Nodules</subject><subject>Pathogenesis</subject><subject>Radiology</subject><subject>Short Report</subject><subject>Substantia alba</subject><subject>Tuberous sclerosis</subject><issn>0028-3940</issn><issn>1432-1920</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kcFO3DAQhq2qFWy3vEAPyFIvvQTGdrJOuKHVtiCtxKU9W44z2TV17MVOoLw93i4FiQOH8Yw03_wz1k_IVwZnDECeJwAuygI4y7EoZVF9IDNWCl6whsNHMsv9uhBNCcfkc0q3ACCkkEfkWIiyZiBhRnYrv9XeWL-h5jGNhbN_kDpMNvhEQ0_HLdKHrR2RDnocMVLr6Ti1GMOUaDIuF8kmasKwc_j3gmrqwz066nGKIerOBhc21mhHe-u7vOYL-dRrl_DkOc_J7x-rX8urYn3z83p5uS6MkNVYLDSITnNmsBFNXbUModIdVB0YWTdYCQmM9a3QNRhmYMGapu3bUnPecwkLEHPy_aC7i-FuwjSqwSaDzmmP-XbFyxp4U5d8j357g96GKfp8neIVrwWT-ckUP1AmfzlF7NUu2kHHR8VA7f1QBz9U9kP980NVeej0WXpqB-xeRv4bkAFxAFJu-Q3G193vyD4Bm3GWBQ</recordid><startdate>20210601</startdate><enddate>20210601</enddate><creator>D’Amico, Alessandra</creator><creator>Perillo, Teresa</creator><creator>Russo, Carmela</creator><creator>Ugga, Lorenzo</creator><creator>Melis, Daniela</creator><creator>Santoro, Claudia</creator><creator>Piluso, Giulio</creator><creator>Cinalli, Giuseppe</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7TK</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-3840-7637</orcidid></search><sort><creationdate>20210601</creationdate><title>Enhancing cyst-like lesions of the white matter in tuberous sclerosis complex: a novel neuroradiological finding</title><author>D’Amico, Alessandra ; Perillo, Teresa ; Russo, Carmela ; Ugga, Lorenzo ; Melis, Daniela ; Santoro, Claudia ; Piluso, Giulio ; Cinalli, Giuseppe</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-6a03da21ce93985b1e05ad05d0c789e537011fb3a80c1c06199bfb4a22f270603</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Astrocytoma</topic><topic>Cysts</topic><topic>Gadolinium</topic><topic>Imaging</topic><topic>Lesions</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Neurology</topic><topic>Neuroradiology</topic><topic>Neurosciences</topic><topic>Neurosurgery</topic><topic>Nodules</topic><topic>Pathogenesis</topic><topic>Radiology</topic><topic>Short Report</topic><topic>Substantia alba</topic><topic>Tuberous sclerosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>D’Amico, Alessandra</creatorcontrib><creatorcontrib>Perillo, Teresa</creatorcontrib><creatorcontrib>Russo, Carmela</creatorcontrib><creatorcontrib>Ugga, Lorenzo</creatorcontrib><creatorcontrib>Melis, Daniela</creatorcontrib><creatorcontrib>Santoro, Claudia</creatorcontrib><creatorcontrib>Piluso, Giulio</creatorcontrib><creatorcontrib>Cinalli, Giuseppe</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Neuroradiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>D’Amico, Alessandra</au><au>Perillo, Teresa</au><au>Russo, Carmela</au><au>Ugga, Lorenzo</au><au>Melis, Daniela</au><au>Santoro, Claudia</au><au>Piluso, Giulio</au><au>Cinalli, Giuseppe</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Enhancing cyst-like lesions of the white matter in tuberous sclerosis complex: a novel neuroradiological finding</atitle><jtitle>Neuroradiology</jtitle><stitle>Neuroradiology</stitle><addtitle>Neuroradiology</addtitle><date>2021-06-01</date><risdate>2021</risdate><volume>63</volume><issue>6</issue><spage>971</spage><epage>974</epage><pages>971-974</pages><issn>0028-3940</issn><eissn>1432-1920</eissn><abstract>Tuberous sclerosis complex (TSC) is an autosomal dominant condition clinically presenting with heterogenous clinical features. Multiple neuroradiological manifestations have been associated with TSC, such as tubers, radial migration lines, subependymal nodules, subependymal giant cell astrocytomas, and cyst-like lesions of the white matter (CLLWMs). The latter have been described as non-enhancing well-defined cysts whose pathogenesis is still unknown. We describe 2 TSC patients with CLLWM showing contrast enhancement after Gadolinium injection, a previously unreported entity.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>33481070</pmid><doi>10.1007/s00234-021-02647-5</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0002-3840-7637</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-3940 |
| ispartof | Neuroradiology, 2021-06, Vol.63 (6), p.971-974 |
| issn | 0028-3940 1432-1920 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2480298420 |
| source | SpringerLink Journals - AutoHoldings |
| subjects | Astrocytoma Cysts Gadolinium Imaging Lesions Medicine Medicine & Public Health Neurology Neuroradiology Neurosciences Neurosurgery Nodules Pathogenesis Radiology Short Report Substantia alba Tuberous sclerosis |
| title | Enhancing cyst-like lesions of the white matter in tuberous sclerosis complex: a novel neuroradiological finding |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-25T17%3A49%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Enhancing%20cyst-like%20lesions%20of%20the%20white%20matter%20in%20tuberous%20sclerosis%20complex:%20a%20novel%20neuroradiological%20finding&rft.jtitle=Neuroradiology&rft.au=D%E2%80%99Amico,%20Alessandra&rft.date=2021-06-01&rft.volume=63&rft.issue=6&rft.spage=971&rft.epage=974&rft.pages=971-974&rft.issn=0028-3940&rft.eissn=1432-1920&rft_id=info:doi/10.1007/s00234-021-02647-5&rft_dat=%3Cproquest_cross%3E2480298420%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2528317283&rft_id=info:pmid/33481070&rfr_iscdi=true |