Prognostic value of leucine/phenylalanine ratio as an amino acid profile of heart failure

Heart failure (HF) causes a hypercatabolic state that enhances the catabolic activity of branched-chain amino acids (BCAA; leucine, isoleucine, and valine) in the heart and skeletal muscles and reduces protein synthesis in the liver. Consequently, free plasma aromatic amino acids (AAA, tyrosine and...

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Veröffentlicht in:	Heart and vessels 2021-07, Vol.36 (7), p.965-977
Hauptverfasser:	Hiraiwa, Hiroaki, Okumura, Takahiro, Kondo, Toru, Kato, Toshiaki, Kazama, Shingo, Kimura, Yuki, Ishihara, Toshikazu, Iwata, Etsuo, Shimojo, Masafumi, Kondo, Sayano, Aoki, Soichiro, Kanzaki, Yasunori, Tanimura, Daisuke, Sano, Hiroaki, Awaji, Yoshifumi, Yamada, Sumio, Murohara, Toyoaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Biomedical Engineering and Bioengineering Cardiac Surgery Cardiology Chain branching Congestive heart failure Heart failure Isoleucine Leucine Medicine Medicine & Public Health Metabolism Muscles Original Article Phenylalanine Protein biosynthesis Protein synthesis Regression analysis Skeletal muscle Survival analysis Tyrosine Valine Vascular Surgery
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